--- title: "The Nasdaq Biotechnology Index closed down nearly 2%, with a cumulative decline of over 8.4% this week" description: "The Nasdaq Biotechnology Index fell nearly 2% on Friday, with a cumulative decline of over 8.4% for the week. Among the constituent stocks, Iovance Biotherapeutics plummeted 44.80%, Savara fell 11.49%" type: "news" locale: "en" url: "https://longbridge.com/en/news/239636107.md" published_at: "2025-05-09T20:48:14.000Z" --- # The Nasdaq Biotechnology Index closed down nearly 2%, with a cumulative decline of over 8.4% this week > The Nasdaq Biotechnology Index fell nearly 2% on Friday, with a cumulative decline of over 8.4% for the week. Among the constituent stocks, Iovance Biotherapeutics plummeted 44.80%, Savara fell 11.49%, Esperion dropped 10.60%, Lexeo Therapeutics decreased by 10.33%, and Novavax fell 10.29%. In contrast, Alector rose 13.46%, Corvus Pharmaceuticals increased by 32.24%, and Phathom Pharma surged 37.12% On Friday, constituent stock Iovance Biotherapeutics fell by 44.80%, Savara dropped by 11.49%, Esperion decreased by 10.60%, Lexeo Therapeutics fell by 10.33%, and Novavax dropped by 10.29%; Alector, on the other hand, rose by 13.46% to rank third, Corvus Pharmaceuticals increased by 32.24%, and Phathom Pharma rose by 37.12% ### Related Stocks - [ALEC.US - Alector](https://longbridge.com/en/quote/ALEC.US.md) - [SVRA.US - Savara](https://longbridge.com/en/quote/SVRA.US.md) - [NVAX.US - Novavax](https://longbridge.com/en/quote/NVAX.US.md) - [LXEO.US - Lexeo Therapeutics](https://longbridge.com/en/quote/LXEO.US.md) - [ESPR.US - Esperion Therap](https://longbridge.com/en/quote/ESPR.US.md) ## Related News & Research | Title | Description | URL | |-------|-------------|-----| | Alector 在公司演示中展示了新的研发管线进展和脑载体技术 | Alector Inc. 更新了其领导层、研究项目和专有技术,重点介绍了其用于跨越血脑屏障输送疗法的 Alector Brain Carrier (ABC) 技术。该公司正在开发针对阿尔茨海默病和帕金森病等神经退行性疾病的药物候选者。Ale | [Link](https://longbridge.com/en/news/271716884.md) | | Alector Inc. 的首席会计官 Grace Wong-Sarad 报告了普通股的出售 | Alector Inc. 的首席会计官 Grace Wong-Sarad 报告了公司普通股的出售。该公告于 2025 年 12 月 08 日通过 EDGAR 由 Alector Inc. 发布 | [Link](https://longbridge.com/en/news/269005477.md) | | Alector Inc [ALEC] 的总裁 Kenkare-Mitra 出售了 41,687 股 | Alector Inc. 的总裁 Sara Kenkare-Mitra 向公司回售了 41,687 股股票,以支付期权行使费用和税务责任,这一信息在 2025 年 12 月 3 日提交给 SEC 的 Form 4 中披露。她的最终持股为 5 | [Link](https://longbridge.com/en/news/268520387.md) | | Pres Kenkare-Mitra 申请出售 36,914 股 Alector 公司 [ALEC] | Alector Inc 的总裁 Sara Kenkare-Mitra 于 2025 年 12 月 1 日向美国证券交易委员会(SEC)提交了 144 表格,计划出售 36,914 股 Alector Inc 的股票。此次出售将由摩根士丹利史 | [Link](https://longbridge.com/en/news/268161868.md) | | Wong-Sarad 官员申请出售 7,085 股 Alector 公司 [ALEC] | Alector Inc 的官员 Wong-Sarad Grace 于 2025 年 12 月 1 日向美国证券交易委员会(SEC)提交了 144 表格,计划通过摩根士丹利史密斯巴尼 LLC 出售 7,085 股限制性股票。该申请允许在 90 | [Link](https://longbridge.com/en/news/268161859.md) | --- > **Disclaimer**: This article is for reference only and does not constitute any investment advice.