---
title: "Pre-market hot trades in US stocks: Upexi up 12.30% in pre-market; DeFi Development up 10.49% in pre-market"
type: "News"
locale: "en"
url: "https://longbridge.com/en/news/249353725.md"
description: "Upexi pre-market up 12.30%; DeFi Development pre-market up 10.49%; GlucoTrack pre-market up 80.10%; TNF Pharmaceuticals pre-market up 54.06%; Opendoor Tech pre-market up 34.22%"
datetime: "2025-07-21T08:07:53.000Z"
locales:
  - [zh-CN](https://longbridge.com/zh-CN/news/249353725.md)
  - [en](https://longbridge.com/en/news/249353725.md)
  - [zh-HK](https://longbridge.com/zh-HK/news/249353725.md)
generator: "portal-rs"
---

# Pre-market hot trades in US stocks: Upexi up 12.30% in pre-market; DeFi Development up 10.49% in pre-market

**Pre-market Hot Trades in US Stocks**

Upexi pre-market up 12.30%. Based on recent important news:

1.  On July 18, Upexi announced it raised $100 million through a PIPE private placement, led by GSR, rapidly increasing its SOL assets, driving the stock price up 12.3%.

2.  On July 18, Upexi CEO stated that they would continue to increase their holdings in SOL, with the stock price rising 254% since early July.

3.  On July 18, Upexi completed a $150 million convertible bond issuance, holding 1.65 million SOL, with the stock price rising 20%.

DeFi Development pre-market up 10.49%. Based on recent important news:

1.  On July 18, DeFi Development announced the launch of the SOL Reserve Accelerator Program, gaining support from Kraken and others, driving international expansion and stimulating the stock price up 10.49%.

**Top Gainers in Pre-market US Stocks**

GlucoTrack pre-market up 80.10%. Based on recent important news:

1.  On June 23, Baize Medical's dark pool closing price was 25.6% higher than the listing price, increasing market interest in medical stocks, driving GlucoTrack's stock price up.

2.  On June 26, Saint Bella's dark pool closing price was 32% higher than the listing price, with the overall strong performance of the medical industry further boosting GlucoTrack's stock price.

3.  On June 30, Tide Pharmaceuticals' dark pool closing price was 1.8% higher than the listing price, showing continued market attention on medical stocks, supporting GlucoTrack's upward trend.

TNF Pharmaceuticals pre-market up 54.06%. Based on recent important news:

1.  On June 25, Rongchang Bio's core product Taitasip received patent term compensation, with the stock price soaring over 16%, reflecting market optimism about its future growth.

2.  On June 26, Vor Bio performed poorly, laying off 95% of its staff, causing Rongchang Bio's stock price to plummet, indicating market concerns about its collaboration model.

3.  On June 12, China National Pharmaceutical announced it would soon reach a significant licensing deal, with the stock price soaring nearly 18%, reflecting market confidence in its international strategy.

Opendoor Tech pre-market up 34.22%. Based on recent key news:

1.  On July 18, Opendoor's stock price surged due to the meme stock craze and short squeeze, with a pre-market increase of 34.22%.

2.  On July 18, over 60% of shares changed hands in the market, indicating strong investor interest and trading activity.

3.  On July 18, analyst Eric Jackson stated that Opendoor could become a "100x stock," further stimulating market sentiment

### Related Stocks

- [UPXI.US](https://longbridge.com/en/quote/UPXI.US.md)
- [DFDV.US](https://longbridge.com/en/quote/DFDV.US.md)

## Related News & Research

- [Upexi fiscal 2026 net loss widens, driven by unrealized losses on digital assets](https://longbridge.com/en/news/299363220.md)
- [DeFi Development Chief Strategy Officer Daniel Kang acquires 11,000 shares worth $42,680](https://longbridge.com/en/news/296651324.md)
- [DeFi Development Corp. Prices CHAD Preferred Stock Offering](https://longbridge.com/en/news/298345802.md)
- [DeFi Development Corp. Launches CHAD, the First SOL-Backed Digital Credit Instrument, With Participation from Fundstrat’s Tom Lee | DFDV Stock News](https://longbridge.com/en/news/298322870.md)
- [Top Executive Makes Bold Move With Fresh Stake in DeFi Development Corporation](https://longbridge.com/en/news/296663440.md)

---
> **Disclaimer: This article is for reference only and does not constitute any investment advice.**