--- title: "Why Eli Lilly Stock Was Looking Sickly Today" description: "Eli Lilly's stock fell nearly 6%, underperforming the S&P 500's 0.3% drop, primarily due to concerns over the performance of its weight-loss drug Zepbound, following Novo Nordisk's lowered sales and p" type: "news" locale: "en" url: "https://longbridge.com/en/news/250665857.md" published_at: "2025-07-29T22:07:31.000Z" --- # Why Eli Lilly Stock Was Looking Sickly Today > Eli Lilly's stock fell nearly 6%, underperforming the S&P 500's 0.3% drop, primarily due to concerns over the performance of its weight-loss drug Zepbound, following Novo Nordisk's lowered sales and profit guidance. Despite this decline, analysts believe the demand for obesity drugs remains strong, and Eli Lilly's diverse portfolio mitigates risks associated with any single product. One of the more popular stocks in the pharmaceutical sector of late got the cold shoulder from investors on Tuesday. **Eli Lilly** (LLY -5.50%) closed today's trading session down by almost 6% in value, which was notably worse than the 0.3% drop of the bellwether **S&P 500** index. That decline wasn't necessarily Eli Lilly's fault, though. ## Reducing weight, reducing guidance Eli Lilly's recent popularity is due in no small measure to its plunge into the highly lucrative weight-loss drug market. In late 2023, its Zepbound -- essentially the same treatment as its diabetes drug Mounjaro -- was approved to treat obesity, and the company was off to the races. Image source: Getty Images. On Tuesday, though, the standard-bearer for the segment took quite a tumble. That was **Novo Nordisk**, which this morning lowered its guidance for both full-year sales and operating profit. The growth forecast for the former was reduced to 8% to 14% over the 2024 tally (previous guidance range: 13% to 21%). Ditto for operating profit, which is now expected to rise in a range of 10% to 16%. That would be encouraging, if it weren't for the fact that management's preceding prediction was 16% to 24%. Novo Nordisk is known for developing and selling Wegovy, the first GLP-1 drug approved by the U.S. Food and Drug Administration specifically for weight loss. The company has flown to renown and admiration on the wings of that drug, which remains a key product. Investors probably fear that Eli Lilly's Zepbound will also perform worse than expected. ## Not an emergency I don't think anyone should push the panic button on Eli Lilly due to this (or Novo Nordisk, while I'm at it). Demand for obesity drugs remains strong and nearly unlimited, so both Zepbound and Wegovy -- which still benefit from a lack of competitors, at least for now -- should continue to be growth drivers. Also, in the case of Eli Lilly, the sprawling pharmaceutical company has a vast portfolio and a very wide development pipeline, so it's hardly dependent on one drug -- no matter how currently popular that drug might be. ### Related Stocks - [LLY.US - Eli Lilly](https://longbridge.com/en/quote/LLY.US.md) ## Related News & Research | Title | Description | URL | |-------|-------------|-----| | DELL, SPOT, UNH:全球最大的对冲基金正在市场中寻找抄底机会 | 桥水基金(Bridgewater Associates),全球最大的对冲基金,管理资产达 1360 亿美元,在 2025 年第四季度对表现不佳的股票进行了重大投资,包括戴尔(DELL)、Spotify(SPOT)和联合健康(UnitedHe | [Link](https://longbridge.com/en/news/276384705.md) | | 3.5 亿首付款、总额达 85 亿美元!信达生物与礼来合作布局肿瘤免疫新药研发 | 信达生物与礼来达成突破性合作,将联合开发肿瘤及免疫新药。此次交易预付款 3.5 亿美元,总额最高达 85 亿美元。双方摒弃传统授权,采用从零开始的共同研发模式,标志着中国药企创新力获全球顶尖药企深度认可,开启全球战略协作新篇章。 | [Link](https://longbridge.com/en/news/275269682.md) | | “硬件防御” 对冲 AI 焦虑,苹果与纳指相关性创 20 年新低 | AI 浪潮下,苹果因未深度卷入军备竞赛,与纳指相关性创 20 年新低,成为科技股动荡中的 “避风港”。在 AI 投资回报存疑及软件业面临颠覆的焦虑中,苹果凭借不易受冲击的硬件生态逆势突围。尽管存在估值偏高及增长放缓压力,其独特的 “AI 中 | [Link](https://longbridge.com/en/news/276301841.md) | | 沃尔玛四季度财报超预期但盈利指引不及预期,CEO 称 “美国低收入家庭只能勉强维持生计” | 沃尔玛 Q4 营收超预期,新财年盈利指引(每股 2.75-2.85 美元)远低于市场预期的 2.96 美元,显示通胀压力下消费者支出不确定性犹存,拖累股价下跌 1.38%。财报印证 K 型” 分化:高收入家庭驱动增长,低收入群体 “钱包吃紧 | [Link](https://longbridge.com/en/news/276398633.md) | | 谷歌突然发布 Gemini 3.1 Pro:核心推理性能直接翻倍 | 谷歌发布了最新的大模型 Gemini 3.1 Pro,其推理性能较去年发布的 Gemini 3 Pro 翻倍。在 ARC-AGI-2 评测中,Gemini 3.1 Pro 得分 77.1%,显示出强大的推理能力。新模型支持多源数据综合和复杂 | [Link](https://longbridge.com/en/news/276396515.md) | --- > **Disclaimer**: This article is for reference only and does not constitute any investment advice.