---
title: "U.S. stock market intraday update: OSR up 124.29%"
description: "OSR rose 124.29%; HCW Biologics rose 57.93%, with a transaction volume of USD 124 million; ESSA Pharmaceuticals fell 59.23%, with a transaction volume of USD 796.2 million; Ethzilla rose 8.94%, with a"
type: "news"
locale: "en"
url: "https://longbridge.com/en/news/254463947.md"
published_at: "2025-08-25T13:32:55.000Z"
---

# U.S. stock market intraday update: OSR up 124.29%

> OSR rose 124.29%; HCW Biologics rose 57.93%, with a transaction volume of USD 124 million; ESSA Pharmaceuticals fell 59.23%, with a transaction volume of USD 796.2 million; Ethzilla rose 8.94%, with a transaction volume of USD 296.9 million; AbbVie fell 0.06%, with a market value of USD 371.7 billion

**U.S. Stock Market Midday Update**

OSR rose 124.29%, with active trading. Based on recent important news:

1.  On July 8, OSR Holdings obtained a $80 million equity credit line, enhancing the company's financial strength, leading to a rise in stock price.
    
2.  On July 25, OSL Group completed a $300 million equity financing, pushing the stock price up by 5.72%.
    
3.  On August 5, after resuming trading, Shangwei New Materials' stock price surged by 14%, reflecting high market sentiment.
    

**Stocks with High Trading Volume in the Industry**

HCW Biologics rose 57.93%, with a trading volume of $124 million. Based on recent important news:

1.  On August 25, the company’s immune checkpoint inhibitor based on pembrolizumab showed success in IND-enabled studies for solid tumors, activating immune cells and promoting their infiltration, leading to a significant stock price increase of 57.93%.

ESSA Pharmaceuticals fell 59.23%, with increased trading volume. Based on recent important news:

1.  On July 18, Federal Pharmaceuticals announced a placement of new shares, causing the stock price to drop by 7.15%. This move may affect market confidence in the pharmaceutical industry, leading to a significant decline in ESSA Pharmaceuticals' stock price.
    
2.  On August 1, Kangmei Pharmaceutical experienced a block trade at a discount of 11.37%, impacting market confidence in the pharmaceutical industry.
    
3.  On August 19, frequent block trades in Borui Pharmaceuticals led to a 1.97% drop in stock price, affecting market sentiment.
    

Ethzilla rose 8.94%, with increased trading volume. Based on recent important news:

1.  On August 25, ETHZilla announced a $250 million stock buyback plan, effective immediately, pushing the stock price up by 6.06%.
    
2.  On August 23, ETHZilla raised the scale of its stock issuance to $10 billion to support the purchase of ETH, enhancing market confidence.
    
3.  On August 22, ETHZilla shareholders applied for the issuance of 74.8 million convertible stocks, leading to stock price fluctuations.
    

**Stocks with High Market Capitalization in the Industry**

AbbVie fell 0.06%, with increased trading volume. Based on recent important news:

1.  On August 22, AbbVie announced that its alopecia treatment drug Rinvoq achieved its primary goals in late-stage trials, showing significant efficacy and manageable risks, stabilizing the stock price.
    
2.  On August 25, AbbVie announced the acquisition of Gilgamesh Pharmaceuticals' antidepressant for $1.2 billion, expanding its psychiatry product line and enhancing market confidence.
    
3.  On August 24, analysts predicted that AbbVie's Skyrizi and Rinvoq would drive the company's long-term growth, despite Humira losing patent protection, still achieving revenue growth

### Related Stocks

- [OSRH.US - OSR](https://longbridge.com/en/quote/OSRH.US.md)

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> **Disclaimer**: This article is for reference only and does not constitute any investment advice.