--- title: "Top 5 US Stock Gainers/Losers (>100B) (10.7)" description: "Biodexa Pharmaceuticals(BDRX) rose 24.89%, with a trading turnover 1.0 Million USD, and a year-to-date fell 79.6%. AppLovin(APP) rose 7.64%, with a trading turnover 7.3 Billion USD, and a year-to-date" type: "news" locale: "en" url: "https://longbridge.com/en/news/260210434.md" published_at: "2025-10-07T22:00:51.000Z" --- # Top 5 US Stock Gainers/Losers (>100B) (10.7) > Biodexa Pharmaceuticals(BDRX) rose 24.89%, with a trading turnover 1.0 Million USD, and a year-to-date fell 79.6%. AppLovin(APP) rose 7.64%, with a trading turnover 7.3 Billion USD, and a year-to-date rose 95.1%. Lam Research(LRCX) fell 5.9%, with a trading turnover 2.4 Billion USD, and a year-to-date rose 95.8%. Applied Materials(AMAT) fell 5.52%, with a trading turnover 2.3 Billion USD, and a year-to-date rose 31.1%. NASDAQ Composite Index has fell 0.67%, with a year-to-date rose 18%; S&P 500 has fell 0.38%, with a year-to-date rose 14.2%; Dow Jones Industrial Average has fell 0.2%, with a year-to-date rose 9.5%. Biodexa Pharmaceuticals(BDRX) rose 24.89%, with a trading turnover 1.0 Million USD, and a year-to-date fell 79.6%. AppLovin(APP) rose 7.64%, with a trading turnover 7.3 Billion USD, and a year-to-date rose 95.1%. Lam Research(LRCX) fell 5.9%, with a trading turnover 2.4 Billion USD, and a year-to-date rose 95.8%. Applied Materials(AMAT) fell 5.52%, with a trading turnover 2.3 Billion USD, and a year-to-date rose 31.1%. ### Related Stocks - [BDRX.US - Biodexa Pharmaceuticals](https://longbridge.com/en/quote/BDRX.US.md) - [APP.US - AppLovin](https://longbridge.com/en/quote/APP.US.md) - [AMD.US - AMD](https://longbridge.com/en/quote/AMD.US.md) - [DELL.US - Dell Tech](https://longbridge.com/en/quote/DELL.US.md) - [GILD.US - Gilead Sciences](https://longbridge.com/en/quote/GILD.US.md) - [LRCX.US - Lam Research](https://longbridge.com/en/quote/LRCX.US.md) - [AMAT.US - Applied Materials](https://longbridge.com/en/quote/AMAT.US.md) - [KLAC.US - KLA](https://longbridge.com/en/quote/KLAC.US.md) - [TSLA.US - Tesla](https://longbridge.com/en/quote/TSLA.US.md) - [ASML.US - ASML](https://longbridge.com/en/quote/ASML.US.md) ## Related News & Research | Title | Description | URL | |-------|-------------|-----| | 特斯拉首辆 Cybercab 下线:没有方向盘和踏板的汽车终于来了 | 特斯拉宣布,首辆赛博无人驾驶电动车 Tesla Cybercab 在美国得州超级工厂正式下线。风险提示及免责条款 市场有风险,投资需谨慎。本文不构成个人投资建议,也未考虑到个别用户特殊的投资目标、财务状况或需要。用户应考虑本文中的任何意见、 | [Link](https://longbridge.com/en/news/276188665.md) | | Top 5 美股千亿以上公司涨跌幅(2月18日) | AppLovin(APP) 涨 7.44%,成交额 22.9 亿美元,年内累计跌 40%。 Shopify (SHOP) 涨 7.13%,成交额 22.6 亿美元,年内累计跌 24.4%。 派拓网络 (PANW) 跌 6.82%,成交额 4 | [Link](https://longbridge.com/en/news/276277822.md) | | 应用材料的一位高管出售了 5000 股股票 | 应用材料的高级副总裁兼首席财务官 Brice Hill 于 2026 年 2 月 17 日以每股 361.2124 美元的价格出售了 5,000 股普通股,交易总额为 1,806,062 美元。交易后,他仍持有 138,565 股,其中包括 | [Link](https://longbridge.com/en/news/276286312.md) | | 期权热点|周二 APP 跌 3%,部分看跌期权飙升 150% | 美东时间 02 月 17 日,APP 期权总成交 97736 张,看涨期权占比 30%,看跌期权占比 69%。 | [Link](https://longbridge.com/en/news/276195965.md) | | 这些被认为 “更安全” 的芯片股票在今年表现强劲 | 半导体行业的财报评论积极,像应用材料(Applied Materials,AMAT)、泛林集团(Lam Research,LRCX)和科磊(KLA,KLAC)等公司都发出了强劲需求的信号。应用材料预计到 2026 年,其半导体系统业务将增长 | [Link](https://longbridge.com/en/news/275982144.md) | --- > **Disclaimer**: This article is for reference only and does not constitute any investment advice.