--- title: "Hong Kong Stock Movement: XUANZHUBIO-B surged 21.41%, driven by dual tumor digestion boosting commercialization explosion" description: "XUANZHUBIO-B surged 21.41%; CSPC Pharmaceutical Group fell 1.44%, with a transaction volume of HKD 534 million; China National Pharmaceutical Group fell 0.54%, with a transaction volume of HKD 398 mil" type: "news" locale: "en" url: "https://longbridge.com/en/news/261996996.md" published_at: "2025-10-21T07:37:41.000Z" --- # Hong Kong Stock Movement: XUANZHUBIO-B surged 21.41%, driven by dual tumor digestion boosting commercialization explosion > XUANZHUBIO-B surged 21.41%; CSPC Pharmaceutical Group fell 1.44%, with a transaction volume of HKD 534 million; China National Pharmaceutical Group fell 0.54%, with a transaction volume of HKD 398 million; Heng Rui Medicine fell 1.20%, with a transaction volume of HKD 228 million; Hansoh Pharmaceutical fell 1.32%, with a market value of HKD 217.6 billion **Hong Kong Stock Movement** XUANZHUBIO-B surged 21.41%. According to recent important news: 1. On October 21, XUANZHUBIO-B rose over 14% in the afternoon, reaching a high of HKD 38.8, an increase of over 234% from the IPO price of HKD 11.6. The company has more than ten drug assets actively under development, covering digestive system diseases, tumors, and non-alcoholic fatty liver disease (NASH), including three NDA-approved assets. This news significantly boosted the stock price. Source: Dolphin Research APP 2. On October 21, Dolphin Research APP pointed out that with the dual drivers of digestion and tumors, XUANZHUBIO is expected to enter a commercialization explosion period in 2025. The core tumor drugs Pyrotinib and Dirocitinib have been consecutively approved, along with the previously approved proton pump inhibitor Anaprazole Sodium, forming a commercial "three-horse carriage" product matrix that has gained market recognition. Source: Dolphin Research APP 3. On October 18, traditional Chinese medicine varieties such as Niuhuang Qinggan Capsules received secondary protection approval, prompting companies to increase R&D investment and enhance product competitiveness. This news has a positive impact on the development of the traditional Chinese medicine industry. Source: Artery Network **Stocks with High Trading Volume in the Industry** Shiyao Group fell 1.44%. According to recent important news: 1. On October 20, Shiyao Group's JSKN003, developed in collaboration with CanSino Biologics, received breakthrough therapy designation from the National Medical Products Administration for the treatment of HER2-positive advanced colorectal cancer patients. This news caused stock price fluctuations, with a trading volume of HKD 534 million. Source: Caihua News 2. On October 18, Shiyao Group made progress in its patent dispute in the United States, as the U.S. Patent and Trademark Office accepted Shiyao Group's request to invalidate Lepu Biotech's patent. This event may affect market confidence in Shiyao Group. Source: Dolphin Research 3. On October 20, Shiyao Group's shareholder equity disclosure showed slight changes in shareholding ratios, which may attract market attention. Source: Dolphin Research China Biopharmaceutical fell 0.54%. According to recent news: 1. On October 21, China Biopharmaceutical announced the interim analysis results of the Phase III clinical study of Cumosil Capsules for HR+/HER2- advanced breast cancer at the 2025 European Society for Medical Oncology Congress. The drug showed significant efficacy, delaying clinical resistance issues and reducing bone marrow suppression, becoming a potential best-in-class therapy. This news caused stock price fluctuations. 2. On October 19, research results showed that the median overall survival of Cumosil trial participants reached 35.81 months, setting a historical high and providing new treatment directions for refractory breast cancer patients. This news further influenced market sentiment. 3. On October 21, investment banks rated China Biopharmaceutical primarily as a buy, with 13 investment banks giving buy ratings in the past 90 days, and the average target price set at HKD 10.07 CMB International's latest research report gives a buy rating with a target price of HKD 9.4. This rating information has an impact on the stock price. The chemical pharmaceutical industry has performed strongly recently, with significant capital inflow. Hengrui Medicine fell by 1.20%. According to recent important news: 1. On October 18, Hengrui Medicine announced an international patent application titled "Method for Treating TSLP-Related Inflammatory Diseases with Anti-TSLP Antibodies," demonstrating the company's ongoing investment in R&D, which may have a positive impact on the stock price. Data source: Qichacha 2. On October 20, Hengrui's oncology division achieved a technological breakthrough in the global market, successfully entering the international market, further consolidating its leading position in cancer treatment, which may boost market confidence. Data source: Hengrui Medicine 3. No other significant news recently. The pharmaceutical industry is highly competitive, with increased R&D investment. **Stocks ranked among the top in industry market capitalization** Hansoh Pharmaceutical fell by 1.32%. According to recent important news: 1. On October 20, Hansoh Pharmaceutical signed a licensing agreement for HS-20110 with Roche, receiving an upfront payment of USD 80 million and up to USD 1.45 billion in milestone payments, driving stock price fluctuations. Source: Haitong International 2. On October 20, Nomura Securities raised its revenue and profit forecasts for Hansoh Pharmaceutical for 2026, with a slight increase in the target price to HKD 35.50, maintaining a neutral rating. Source: Nomura Securities 3. On October 18, Hansoh Pharmaceutical received an AA rating in the ESG ranking of the Huazheng Index, ranking 4th among Hong Kong-listed pharmaceutical companies. Source: Huazheng Index. 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