Eledon Pharmaceuticals Reports Promising Early Results for Tegoprubart in Islet Transplant Trial for Type 1 Diabetes

Reuters
2025.11.18 21:05
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Eledon Pharmaceuticals announced promising preliminary results for tegoprubart, an investigational anti-CD40L antibody, in an islet transplant trial for type 1 diabetes. Conducted at the University of Chicago Medicine’s Transplant Institute, the trial showed all six patients in the preliminary cohort achieved insulin independence. The study is funded by Breakthrough T1D, with further research support committed. Results were presented at the Rachmiel Levine-Arthur Riggs Diabetes Research Symposium in Los Angeles.