Syndax Reports Revumenib Achieves 92% Complete Remission Rate in Newly Diagnosed AML Trial

Reuters
2025.12.08 11:50
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Syndax Pharmaceuticals Inc. announced at the ASH Annual Meeting that its menin inhibitor, Revuforj® (revumenib), achieved a 92% complete remission rate in a Phase 1 trial for newly diagnosed AML patients. The trial combined revumenib with intensive chemotherapy. Additional studies showed a 77% overall response rate in relapsed/refractory leukemia patients and positive outcomes in post-transplant maintenance and combination therapies. These findings highlight the potential of revumenib in acute leukemia treatment.