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Shares of Vertex Pharmaceuticals Inc. (VRTX) rallied 1.75% to $444.64 Wednesday, on what proved to be an all-around great trading session for the stock market, with the S&amp;P 500 Index  rising 0.67% to 6,886.68 and the Dow Jones Industrial Average  rising 1.05% to 48,057.75.
The stock's rise snapped a four-day losing streak.
Vertex Pharmaceuticals Inc. closed 14.44% short of its 52-week high of $519.68, which the company achieved on March 14th.
The stock demonstrated a mixed performance when compared to some of its competitors Wednesday, as AbbVie Inc. (ABBV) rose 0.98% to $225.18, Krystal Biotech Inc. (KRYS) rose 2.17% to $239.72, and Arcturus Therapeutics Holdings Inc. (ARCT) rose 6.53% to $7.67.
Trading volume (995,627) remained 414,067 below its 50-day average volume of 1.4 M.
Data source: Dow Jones Market Data, FactSet. Data compiled December 10, 2025.
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(END) Dow Jones Newswires
12-10-25 1639ET

VERX

<p>Vertex Pharmaceuticals Inc. (VRTX) stock rose 1.75% to $444.64, outperforming some competitors during a strong trading session. The S&P 500 and Dow Jones also saw gains. Despite the rise, VRTX remains 14.44% below its 52-week high. Trading volume was below the 50-day average. Competitors like AbbVie, Krystal Biotech, and Arcturus Therapeutics also saw stock increases.</p>

Vertex Pharmaceuticals Inc. Stock Outperforms Competitors On Strong Trading Day