<div id="readability-page-1"><div>Stokes Frank Chief Financial Officer of Castle Biosciences Inc [CSTL] filed a Form 4 on December 11, 2025 with the Securities and Exchange Commission disclosing the following changes in ownership:<div><table><tbody><tr><th>Date</th><th>Transaction</th><th>Shares</th><th>Price</th><th>Value</th></tr><tr><td>12/9/25-12/10/25</td><td>Exercise</td><td>20,786</td><td>$0.00</td><td>N/A</td></tr><tr><td>12/9/25-12/10/25</td><td>Surrender(1)</td><td>9,292</td><td>$38.18</td><td>$354,784</td></tr></tbody></table></div>Ending Holdings: 54,822 - Direct<ul><li>(1)</li><li>Surrender of shares back to company to pay option exercise cost and/or resulting tax liability.</li></ul>For a free trial, or to learn more about our insider trading analysis and data services, please visit http://www.washingtonservice.com or contact us at (301) 913-5100 or send an email to info@washingtonservice.com.Founded in 1970, The Washington Service provides securities professionals with financial, economic and public policy research and data. </div></div>

CSTL

CFO Stokes Frank of Castle Biosciences Inc filed a Form 4 with the SEC, disclosing changes in ownership. He exercised 20,786 shares and surrendered 9,292 shares at $38.18 each to cover option exercise costs and tax liabilities. His ending holdings are 54,822 shares directly. This transaction was reported on December 11, 2025.

CFO Stokes Acquires 11,494 Of Castle Biosciences Inc [CSTL]