---
title: "The Nasdaq Deep Tech Index closed down about 2.3%, underperforming the three major U.S. stock indice"
description: "The Nasdaq Deep Tech Index closed down about 2.3%, underperforming the three major U.S. stock indices. Among the constituent stocks, Immuneering fell 43.22%, CorMedix fell 32.77%, Sionna Therapeutics "
type: "news"
locale: "en"
url: "https://longbridge.com/en/news/271985555.md"
published_at: "2026-01-08T21:25:51.000Z"
---

# The Nasdaq Deep Tech Index closed down about 2.3%, underperforming the three major U.S. stock indice

> The Nasdaq Deep Tech Index closed down about 2.3%, underperforming the three major U.S. stock indices. Among the constituent stocks, Immuneering fell 43.22%, CorMedix fell 32.77%, Sionna Therapeutics fell 15.32%, Absci fell 14.43%, and Vanda Pharmaceuticals fell 14.05%. Xeris Pharmaceuticals rose 12.62%, Erasca rose 12.77%, Ardelyx rose 19.90%, and Enliven Therapeutics rose 50.36%

The Nasdaq Deep Technology Index closed down about 2.3%, underperforming the three major U.S. stock indices. Among the constituent stocks, Immuneering fell 43.22%, CorMedix fell 32.77%, Sionna Therapeutics fell 15.32%, Absci fell 14.43%, and Vanda Pharmaceuticals fell 14.05%. Xeris Pharmaceuticals rose 12.62%, Erasca rose 12.77%, Ardelyx rose 19.90%, and Enliven Therapeutics rose 50.36%

### Related Stocks

- [ERAS.US - Erasca](https://longbridge.com/en/quote/ERAS.US.md)
- [ELVN.US - Enliven Therapeutics](https://longbridge.com/en/quote/ELVN.US.md)

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> **Disclaimer**: This article is for reference only and does not constitute any investment advice.
