---
title: "The Nasdaq Deep Tech Index closed down about 2.3%, underperforming the three major U.S. stock indice"
description: "The Nasdaq Deep Tech Index closed down about 2.3%, underperforming the three major U.S. stock indices. Among the constituent stocks, Immuneering fell 43.22%, CorMedix fell 32.77%, Sionna Therapeutics "
type: "news"
locale: "en"
url: "https://longbridge.com/en/news/271985555.md"
published_at: "2026-01-08T21:25:51.000Z"
---

# The Nasdaq Deep Tech Index closed down about 2.3%, underperforming the three major U.S. stock indice

> The Nasdaq Deep Tech Index closed down about 2.3%, underperforming the three major U.S. stock indices. Among the constituent stocks, Immuneering fell 43.22%, CorMedix fell 32.77%, Sionna Therapeutics fell 15.32%, Absci fell 14.43%, and Vanda Pharmaceuticals fell 14.05%. Xeris Pharmaceuticals rose 12.62%, Erasca rose 12.77%, Ardelyx rose 19.90%, and Enliven Therapeutics rose 50.36%

The Nasdaq Deep Technology Index closed down about 2.3%, underperforming the three major U.S. stock indices. Among the constituent stocks, Immuneering fell 43.22%, CorMedix fell 32.77%, Sionna Therapeutics fell 15.32%, Absci fell 14.43%, and Vanda Pharmaceuticals fell 14.05%. Xeris Pharmaceuticals rose 12.62%, Erasca rose 12.77%, Ardelyx rose 19.90%, and Enliven Therapeutics rose 50.36%

### Related Stocks

- [ERAS.US - Erasca](https://longbridge.com/en/quote/ERAS.US.md)
- [ELVN.US - Enliven Therapeutics](https://longbridge.com/en/quote/ELVN.US.md)

## Related News & Research

| Title | Description | URL |
|-------|-------------|-----|
| Enliven Therapeutics Chief Scientific Officer Joseph P. Lyssikatos Reports Disposal of Common Shares | Joseph P. Lyssikatos, Chief Scientific Officer of Enliven Therapeutics Inc., has reported the disposal of common shares  | [Link](https://longbridge.com/en/news/275523266.md) |
| Erasca Touts Early ERAS-0015 Responses, Potency Edge in Guggenheim Fireside Chat | Erasca (NASDAQ:ERAS) executives discussed early clinical signals and their RAS-focused pipeline during a Guggenheim fire | [Link](https://longbridge.com/en/news/275937678.md) |
| Smartcraft ASA - Smartcraft Group AB (Publ) Has Been Approved For Listing On Nasdaq Stockholm | Smartcraft ASA :SMARTCRAFT ASA - SMARTCRAFT GROUP AB (PUBL) HAS BEEN APPROVED FOR LISTING ON NASDAQ STOCKHOLM | [Link](https://longbridge.com/en/news/275783474.md) |
| Medexus Pharmaceuticals reports Q3 results | Medexus Pharmaceuticals reports Q3 results | [Link](https://longbridge.com/en/news/275670725.md) |
| Apellis Pharmaceuticals, Inc. $APLS Shares Sold by Savant Capital LLC | Savant Capital LLC reduced its stake in Apellis Pharmaceuticals, Inc. (NASDAQ: APLS) by 50.7% in Q3, now holding 48,886  | [Link](https://longbridge.com/en/news/275591859.md) |

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> **Disclaimer**: This article is for reference only and does not constitute any investment advice.