---
title: "Top 5 US Stock Gainers/Losers (>100B) (2.23)"
description: "Agnico Eagle Mines(AEM) rose 5.36%, with a trading turnover 637.0 Million USD, and a year-to-date rose 41.9%. Eli Lilly(LLY) rose 4.86%, with a trading turnover 5.0 Billion USD, and a year-to-date fel"
type: "news"
locale: "en"
url: "https://longbridge.com/en/news/276650697.md"
published_at: "2026-02-23T22:00:51.000Z"
---

# Top 5 US Stock Gainers/Losers (>100B) (2.23)

> Agnico Eagle Mines(AEM) rose 5.36%, with a trading turnover 637.0 Million USD, and a year-to-date rose 41.9%. Eli Lilly(LLY) rose 4.86%, with a trading turnover 5.0 Billion USD, and a year-to-date fell 1.3%. Novo Nordisk AS(NVO) fell 16.43%, with a trading turnover 3.9 Billion USD, and a year-to-date fell 22.1%. IBM(IBM) fell 13.15%, with a trading turnover 4.5 Billion USD, and a year-to-date fell 24.2%.

NASDAQ Composite Index has fell 1.13%, with a year-to-date fell 2.6%; S&P 500 has fell 1.04%, with a year-to-date fell 0.1%; Dow Jones Industrial Average has fell 1.66%, with a year-to-date rose 1.5%.

Agnico Eagle Mines(AEM) rose 5.36%, with a trading turnover 637.0 Million USD, and a year-to-date rose 41.9%.

Eli Lilly(LLY) rose 4.86%, with a trading turnover 5.0 Billion USD, and a year-to-date fell 1.3%.

Novo Nordisk AS(NVO) fell 16.43%, with a trading turnover 3.9 Billion USD, and a year-to-date fell 22.1%.

IBM(IBM) fell 13.15%, with a trading turnover 4.5 Billion USD, and a year-to-date fell 24.2%.

### Related Stocks

- [AEM.US - Agnico Eagle Mines](https://longbridge.com/en/quote/AEM.US.md)
- [LLY.US - Eli Lilly](https://longbridge.com/en/quote/LLY.US.md)
- [GLW.US - Corning](https://longbridge.com/en/quote/GLW.US.md)
- [SCCO.US - Southern Copper](https://longbridge.com/en/quote/SCCO.US.md)
- [ABT.US - Abbott Laboratories](https://longbridge.com/en/quote/ABT.US.md)
- [NVO.US - Novo Nordisk AS](https://longbridge.com/en/quote/NVO.US.md)
- [IBM.US - IBM](https://longbridge.com/en/quote/IBM.US.md)
- [APP.US - AppLovin](https://longbridge.com/en/quote/APP.US.md)
- [COF.US - Capital One Financial](https://longbridge.com/en/quote/COF.US.md)
- [AXP.US - American Express](https://longbridge.com/en/quote/AXP.US.md)

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|-------|-------------|-----|
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> **Disclaimer**: This article is for reference only and does not constitute any investment advice.