---
title: "Top 10 US Stock Losers (2.23)"
description: "Novo Nordisk AS(NVO) fell 16.43%, with a trading turnover 3.9 Billion USD, and a year-to-date fell 22.1%. GRAIL(GRAL) fell 14.3%, with a trading turnover 235.2 Million USD, and a year-to-date fell 49."
type: "news"
locale: "en"
url: "https://longbridge.com/en/news/276650718.md"
published_at: "2026-02-23T22:01:01.000Z"
---

# Top 10 US Stock Losers (2.23)

> Novo Nordisk AS(NVO) fell 16.43%, with a trading turnover 3.9 Billion USD, and a year-to-date fell 22.1%. GRAIL(GRAL) fell 14.3%, with a trading turnover 235.2 Million USD, and a year-to-date fell 49.7%. IBM(IBM) fell 13.15%, with a trading turnover 4.5 Billion USD, and a year-to-date fell 24.2%.

NASDAQ Composite Index has fell 1.13%, with a year-to-date fell 2.6%; S&P 500 has fell 1.04%, with a year-to-date fell 0.1%; Dow Jones Industrial Average has fell 1.66%, with a year-to-date rose 1.5%.

Novo Nordisk AS(NVO) fell 16.43%, with a trading turnover 3.9 Billion USD, and a year-to-date fell 22.1%.

GRAIL(GRAL) fell 14.3%, with a trading turnover 235.2 Million USD, and a year-to-date fell 49.7%.

IBM(IBM) fell 13.15%, with a trading turnover 4.5 Billion USD, and a year-to-date fell 24.2%.

### Related Stocks

- [NVO.US - Novo Nordisk AS](https://longbridge.com/en/quote/NVO.US.md)
- [GRAL.US - GRAIL](https://longbridge.com/en/quote/GRAL.US.md)
- [IBM.US - IBM](https://longbridge.com/en/quote/IBM.US.md)
- [RNG.US - Ringcentral](https://longbridge.com/en/quote/RNG.US.md)
- [STEP.US - Stepstone](https://longbridge.com/en/quote/STEP.US.md)
- [SLM.US - SLM](https://longbridge.com/en/quote/SLM.US.md)
- [LMND.US - Lemonade](https://longbridge.com/en/quote/LMND.US.md)
- [TENB.US - Tenable](https://longbridge.com/en/quote/TENB.US.md)
- [COMP.US - Compass](https://longbridge.com/en/quote/COMP.US.md)
- [MDB.US - MongoDB](https://longbridge.com/en/quote/MDB.US.md)

## Related News & Research

| Title | Description | URL |
|-------|-------------|-----|
| IBM Stock Is Trending After Crating 13% And Claude-Maker Anthropic Is The Reason Why: Here's What Happened | IBM shares fell 13% after Anthropic's Claude Code AI tool raised concerns about potential disruption to IBM's legacy mai | [Link](https://longbridge.com/en/news/276674951.md) |
| Novo Nordisk board proposes re-election of Lars Rebien Sorensen as chair | Novo Nordisk board proposes re-election of Lars Rebien Sorensen as chair | [Link](https://longbridge.com/en/news/276440991.md) |
| Key facts: Novo Nordisk Faces Challenges with CagriSema; $35B M&A Plans | J.P. Morgan analysts raised concerns about CagriSema's underperformance, which may affect demand and long-term sales for | [Link](https://longbridge.com/en/news/276670594.md) |
| Novo Nordisk's CagriSema Fails to Meet Primary Endpoint in Phase 3 Obesity Trial | Novo Nordisk's CagriSema Fails to Meet Primary Endpoint in Phase 3 Obesity Trial | [Link](https://longbridge.com/en/news/276591721.md) |
| Puzo Michael J Has $320,000 Stock Position in Novo Nordisk A/S $NVO | Puzo Michael J significantly reduced its stake in Novo Nordisk A/S (NYSE:NVO) by 86.9% in Q3, now holding 5,775 shares v | [Link](https://longbridge.com/en/news/276447697.md) |

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> **Disclaimer**: This article is for reference only and does not constitute any investment advice.