---
title: "Pre-market hot trades in US stocks: 20/20 Biolabs up 10.53% pre-market; Mercadolibre down 4.29% pre-market"
description: "20/20 Biolabs pre-market up 10.53%; Mercadolibre pre-market down 4.29%; XWELL pre-market up 119.10%; MDJM pre-market up 49.02%; American Rebel pre-market up 27.33%"
type: "news"
locale: "en"
url: "https://longbridge.com/en/news/276865934.md"
published_at: "2026-02-25T09:47:33.000Z"
---

# Pre-market hot trades in US stocks: 20/20 Biolabs up 10.53% pre-market; Mercadolibre down 4.29% pre-market

> 20/20 Biolabs pre-market up 10.53%; Mercadolibre pre-market down 4.29%; XWELL pre-market up 119.10%; MDJM pre-market up 49.02%; American Rebel pre-market up 27.33%

**Pre-market Hot Trades in US Stocks**

20/20 Biolabs, up 10.53% in pre-market trading, has no significant news recently. The trading is active with clear capital flow, and considering the sector and industry trends, the stock shows significant volatility, with specific reasons needing further observation.

Mercadolibre down 4.29% in pre-market trading. Based on recent news,

1.  On February 25, Mercadolibre reported earnings per share of $11.03, below the market expectation of $11.81, leading to a decline in investor sentiment and stock price.
    
2.  On February 25, the company's overall revenue grew 45% year-on-year to $8.76 billion, but profit margins were under pressure, with operating profit margins contracting by more than 3 percentage points year-on-year, raising concerns about its profitability.
    
3.  On February 25, despite the company holding about 40% market share in the Brazilian e-commerce market, ranking first, the global capital market has been swept by the AI boom, leading to a conservative overall market that makes it difficult for the overvalued Mercadolibre to stand out. The market is generally conservative, with significant valuation pressure.
    

**Top Gainers in Pre-market US Stocks**

XWELL up 119.10% in pre-market trading. Based on recent key news:

1.  On February 24, XWELL announced a private placement financing of approximately $31.3 million, in compliance with Nasdaq rules. This move boosted market confidence in the company's financial condition, driving a significant increase in stock price. Source: Reuters
    
2.  On February 24, XWELL confirmed the authenticity of the financing news through GlobeNewswire, further increasing investor confidence. Source: Public Technologies
    
3.  On February 25, Benzinga's stock ranking showed that XWELL exhibited a negative price trend across all time frames, but the financing news temporarily reversed this trend. Source: Benzinga The market reacted positively to the private placement financing, with clear capital inflow.
    

MDJM, up 49.02% in pre-market trading, has no significant news recently. The trading is active with clear capital flow, and considering the sector and industry trends, the stock shows significant volatility, with specific reasons needing further observation.

American Rebel up 27.33% in pre-market trading. Based on recent key news:

1.  On February 25, the CEO of Champion Safe mentioned an increase in demand for high-end safe solutions, driving up American Rebel's stock price. The company designs, manufactures, and sells branded safes and personal safety and self-defense products, with a market capitalization of $1.96 million. Source: Benzinga
    
2.  On February 24, Benzinga's stock ranking showed that American Rebel's price trend was negative across all time frames; nevertheless, the optimistic sentiment in the market regarding its product demand may have driven a short-term increase in stock price. Source: Benzinga The market sees increased demand for high-end security products

### Related Stocks

- [AIDX.US - 20/20 Biolabs](https://longbridge.com/en/quote/AIDX.US.md)
- [MELI.US - Mercadolibre](https://longbridge.com/en/quote/MELI.US.md)

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> **Disclaimer**: This article is for reference only and does not constitute any investment advice.