---
title: "Top 5 US Stock Gainers/Losers (>100B) (3.10)"
type: "News"
locale: "en"
url: "https://longbridge.com/en/news/278620795.md"
description: "Vertex Pharma(VRTX) rose 8.31%, with a trading turnover 1.7 Billion USD, and a year-to-date rose 10.1%. Corning(GLW) rose 5.56%, with a trading turnover 2.3 Billion USD, and a year-to-date rose 55.9%. AppLovin(APP) fell 7.7%, with a trading turnover 3.2 Billion USD, and a year-to-date fell 29.2%. ServiceNow(NOW) fell 4.36%, with a trading turnover 2.6 Billion USD, and a year-to-date fell 23.9%."
datetime: "2026-03-10T22:01:11.000Z"
locales:
  - [zh-CN](https://longbridge.com/zh-CN/news/278620795.md)
  - [en](https://longbridge.com/en/news/278620795.md)
  - [zh-HK](https://longbridge.com/zh-HK/news/278620795.md)
---

# Top 5 US Stock Gainers/Losers (>100B) (3.10)

NASDAQ Composite Index has rose 0.01%, with a year-to-date fell 2.3%; S&P 500 has fell 0.21%, with a year-to-date fell 0.9%; Dow Jones Industrial Average has fell 0.07%, with a year-to-date fell 0.7%.

Vertex Pharma(VRTX) rose 8.31%, with a trading turnover 1.7 Billion USD, and a year-to-date rose 10.1%.

Corning(GLW) rose 5.56%, with a trading turnover 2.3 Billion USD, and a year-to-date rose 55.9%.

AppLovin(APP) fell 7.7%, with a trading turnover 3.2 Billion USD, and a year-to-date fell 29.2%.

ServiceNow(NOW) fell 4.36%, with a trading turnover 2.6 Billion USD, and a year-to-date fell 23.9%.

### Related Stocks

- [VRTX.US](https://longbridge.com/en/quote/VRTX.US.md)
- [GLW.US](https://longbridge.com/en/quote/GLW.US.md)
- [MU.US](https://longbridge.com/en/quote/MU.US.md)
- [BABA.US](https://longbridge.com/en/quote/BABA.US.md)
- [SCCO.US](https://longbridge.com/en/quote/SCCO.US.md)
- [APP.US](https://longbridge.com/en/quote/APP.US.md)
- [NOW.US](https://longbridge.com/en/quote/NOW.US.md)
- [INTU.US](https://longbridge.com/en/quote/INTU.US.md)
- [ACN.US](https://longbridge.com/en/quote/ACN.US.md)
- [PLTR.US](https://longbridge.com/en/quote/PLTR.US.md)

## Related News & Research

- [Corning stock is falling. Why JP Morgan disagrees with the 'blue-sky scenario.'](https://longbridge.com/en/news/283041060.md)
- [$1000 Invested In AppLovin 5 Years Ago Would Be Worth This Much Today](https://longbridge.com/en/news/282905951.md)
- [Cwm LLC Purchases 74,394 Shares of Accenture PLC $ACN](https://longbridge.com/en/news/282964834.md)
- [Soaring Corning stock price faces two major risks](https://longbridge.com/en/news/282199276.md)
- [Border to Coast Pensions Partnership Ltd Makes New $67.99 Million Investment in Intuit Inc. $INTU](https://longbridge.com/en/news/282956556.md)