--- title: "U.S. stock night trading opening fluctuations: XORTX Therapeutics fell 4.95% in night trading; Salesforce fell 4.51% in night trading" type: "News" locale: "en" url: "https://longbridge.com/en/news/283739812.md" description: "XORTX Therapeutics fell 4.95% in after-hours trading; Salesforce fell 4.51% in after-hours trading; Pineapple Financial rose 60.54% in after-hours trading; QuantumScape rose 17.24% in after-hours trading; TOMI Environmental Solutions rose 14.09% in after-hours trading" datetime: "2026-04-23T00:22:19.000Z" locales: - [zh-CN](https://longbridge.com/zh-CN/news/283739812.md) - [en](https://longbridge.com/en/news/283739812.md) - [zh-HK](https://longbridge.com/zh-HK/news/283739812.md) --- # U.S. stock night trading opening fluctuations: XORTX Therapeutics fell 4.95% in night trading; Salesforce fell 4.51% in night trading **U.S. Stock Night Market Opening Movements** XORTX fell 4.95% in the night market. Based on recent key news: 1. On April 21, XORTX Therapeutics announced that it has regained compliance with Nasdaq's minimum bid requirement. The company implemented a 1-for-5 reverse stock split, allowing its stock to trade at or above $1 for 10 consecutive days. Nasdaq issued a compliance letter on April 20, addressing the deficiency in the minimum bid requirement. This news had a positive impact on the stock price but failed to prevent the night market decline. 2. On April 21, technical sentiment signals indicated strong selling, and the market held a pessimistic view on XORTX's stock. Despite the company's market capitalization of CAD 4.16 million, the average trading volume was 936, reflecting low market confidence in its stock. 3. On April 21, XORTX, focused on drug development for gout and progressive kidney disease, announced it received a Nasdaq compliance letter confirming that the company has met the minimum bid requirement. Although this news was positive, it did not reverse the downward trend in the stock price. Market sentiment towards biotech stocks remains low, with significant capital outflows. Salesforce fell 4.51% in the night market. Based on recent key news: 1. On April 22, Salesforce partnered with Google Cloud to launch an AI intelligent agent that can operate across both platforms, enhancing workflow efficiency. This move boosted the stock price, but concerns remain about the long-term impact of AI on its core business. 2. On April 21, technical analysis showed that Salesforce's stock price remains below the long-term trend line. Although short-term demand has improved, overall market sentiment remains cautious. 3. On April 22, concerns intensified regarding the potential reduction in employee license demand due to AI tools, affecting future sales and profit margins, leading to pressure on the stock price. Tech stocks performed strongly overall, with noticeable capital inflows. **Top Gaining Stocks in the U.S. Night Market** Pineapple Financial rose 60.54% in the night market. Based on recent key news: 1. On April 22, Pineapple Financial announced an expansion of its stock buyback program to $15 million, driving the stock price up. The company's board approved this expansion plan, demonstrating confidence in the company's future development, resulting in a significant increase in stock price. 2. On April 21, Pineapple's earnings call revealed that the company is tightening operations, cutting costs, and exploring new digital revenue streams. Despite facing execution and macro risks, if management can achieve breakeven targets, the current valuation gap may narrow, attracting investor attention. 3. On April 23, as a leading fintech company in Canada, Pineapple continues to play a technological intermediary role in the housing finance market. The company combines innovative fintech with traditional mortgage services, attracting industry professionals and potential homebuyers, further enhancing market confidence. Innovation in the fintech industry is accelerating, and risks need to be monitored QuantumScape rose 17.24% in after-hours trading. Based on recent news, 4. On April 22, QuantumScape announced its Q1 2026 financial report, showing a loss of $0.16 per share, better than the expected loss of $0.18, driving the stock price up by 14%. 5. On April 22, QuantumScape announced the completion of a technology assessment with another global top ten automotive manufacturer, further boosting market confidence, with the stock price rising by 10.56%. 6. On April 22, QuantumScape attracted significant strategic investments and formed partnerships with leading automotive manufacturers, further driving the stock price up. The industry performed well overall, with noticeable capital inflows. TOMI rose 14.09% in after-hours trading. Based on recent key news: 1. On April 22, TOMI Environmental Solutions released a new company announcement, driving the stock price up. The announcement was published via GlobeNewswire and involved the company's future development plans, eliciting a positive market response, with the stock price rising by 14.09%. Source: Public Technologies 2. No other recent news. 3. No other recent news. The environmental protection industry has seen increased attention, with noticeable capital inflows ### Related Stocks - [XRTX.US](https://longbridge.com/en/quote/XRTX.US.md) - [CRM.US](https://longbridge.com/en/quote/CRM.US.md) ## Related News & Research - [Why Salesforce stock is surging today?](https://longbridge.com/en/news/286605553.md) - [If You Invested $100 In Salesforce Stock 20 Years Ago, You Would Have This Much Today](https://longbridge.com/en/news/286829126.md) - [Applied Finance Capital Management LLC Sells 3,485 Shares of Salesforce Inc. $CRM](https://longbridge.com/en/news/286638192.md) - [Salesforce India employee base crosses 17,000 amid AI expansion push](https://longbridge.com/en/news/286934995.md) - [How Heathrow partnered with Salesforce to build a customer-service AI agent](https://longbridge.com/en/news/286601651.md)