---
title: "Lyell Immunopharma | 10-Q: FY2026 Q1 Revenue Misses Estimate at USD 2 K"
type: "News"
locale: "en"
url: "https://longbridge.com/en/news/285432579.md"
datetime: "2026-05-06T20:26:04.000Z"
locales:
  - [zh-CN](https://longbridge.com/zh-CN/news/285432579.md)
  - [en](https://longbridge.com/en/news/285432579.md)
  - [zh-HK](https://longbridge.com/zh-HK/news/285432579.md)
---

# Lyell Immunopharma | 10-Q: FY2026 Q1 Revenue Misses Estimate at USD 2 K

Revenue: As of FY2026 Q1, the actual value is USD 2 K, missing the estimate of USD 4.4 K.

EPS: As of FY2026 Q1, the actual value is USD -1.1, beating the estimate of USD -2.364.

EBIT: As of FY2026 Q1, the actual value is USD -46.46 M.

Lyell Immunopharma, Inc. operates as a single reportable segment, with financial information reviewed on a consolidated basis by its Chief Operating Decision Maker (CODM).

#### Revenue

Revenue was $2 thousand for the three months ended March 31, 2026, a decrease from $7 thousand for the three months ended March 31, 2025. Lyell Immunopharma, Inc. has not generated revenue from product sales as it has no approved products.

#### Operating Expenses

Total operating expenses were $44,263 thousand for the three months ended March 31, 2026, a decrease of $13,111 thousand from $57,374 thousand for the three months ended March 31, 2025. **Research and Development (R&D) Expenses**: R&D expenses decreased by $6,843 thousand, from $43,447 thousand in 2025 to $36,604 thousand in 2026. This reduction was primarily due to a -$7,537 thousand decrease in personnel-related expenses and a -$2,714 thousand reduction in facilities, technology, and depreciation expenses, partially offset by a $3,408 thousand increase in research activities, collaborations, and outside services. **General and Administrative (G&A) Expenses**: G&A expenses decreased by $4,491 thousand, from $14,046 thousand in 2025 to $9,555 thousand in 2026, mainly due to a -$4,000 thousand decrease in personnel costs, including a -$1,500 thousand decrease in stock-based compensation expense. **Other Operating Income, Net**: Other operating income, net increased to $1,896 thousand for the three months ended March 31, 2026, from - $119 thousand for the same period in 2025, primarily due to increased sublease income and reduced losses on property and equipment disposals.

#### Net Loss

Net loss improved to - $24,153 thousand for the three months ended March 31, 2026, compared to - $52,195 thousand for the three months ended March 31, 2025, representing a decrease in net loss of $28,042 thousand.

#### Interest Income, Net

Interest income, net decreased by $1,668 thousand, from $3,862 thousand in 2025 to $2,194 thousand in 2026, driven by decreased interest rates and lower cash equivalent and marketable securities balances.

#### Other Income, Net

Other income, net significantly increased to $17,914 thousand for the three months ended March 31, 2026, from $1,310 thousand for the same period in 2025, primarily due to a $17,600 thousand gain from the change in the fair value of the Securities Purchase Agreement (SPA) put/call asset.

#### Cash Flows

-   **Net Cash Used in Operating Activities**: - $38,510 thousand for the three months ended March 31, 2026, compared to - $54,738 thousand for the three months ended March 31, 2025.
-   **Net Cash Provided by Investing Activities**: $17,378 thousand for the three months ended March 31, 2026, compared to $69,466 thousand for the three months ended March 31, 2025.
-   **Net Cash Provided by Financing Activities**: $51,722 thousand for the three months ended March 31, 2026, compared to $1 thousand for the three months ended March 31, 2025.
-   **Net Increase in Cash, Cash Equivalents and Restricted Cash**: $30,590 thousand for the three months ended March 31, 2026, compared to $14,729 thousand for the three months ended March 31, 2025.

#### Balance Sheet Highlights

-   **Cash, Cash Equivalents and Marketable Securities**: $261,000 thousand as of March 31, 2026, excluding restricted cash.
-   **Total Assets**: $350,626 thousand as of March 31, 2026, up from $340,052 thousand as of December 31, 2025.
-   **Total Liabilities**: $76,961 thousand as of March 31, 2026, down from $91,850 thousand as of December 31, 2025.
-   **Total Stockholders’ Equity**: $273,665 thousand as of March 31, 2026, up from $248,202 thousand as of December 31, 2025.
-   **Accumulated Deficit**: - $1,643,707 thousand as of March 31, 2026.

#### Future Outlook and Strategy

Lyell Immunopharma, Inc. anticipates continued significant operating losses due to ongoing R&D, clinical trials, and manufacturing expansion efforts. The company projects its current cash, cash equivalents, and marketable securities will fund operations for at least the next 12 months. However, additional capital will be required for future development and commercialization, with needs dependent on factors like clinical trial scope, regulatory approvals, and manufacturing costs.

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