---
title: "Tonix Pharmaceuticals Announces Publication in the Peer-Reviewed Journal of Virology Assessing Virulence of the 2022 Outbreak Strain of Mpox in New Animal Models"
type: "News"
locale: "en"
url: "https://longbridge.com/en/news/292775340.md"
description: "Information indicates that clade IIb, a strain from the 2022 outbreak, is significantly less virulent compared to clade IIa, a strain from the 2003 outbreak. The data shows that clade IIb is between 100 to 100,000 times less harmful in terms of its virulence when compared to clade IIa. This highlights a notable difference in the virulence levels between these two clades separated by nearly two decades."
datetime: "2026-07-15T13:06:46.000Z"
locales:
  - [zh-CN](https://longbridge.com/zh-CN/news/292775340.md)
  - [en](https://longbridge.com/en/news/292775340.md)
  - [zh-HK](https://longbridge.com/zh-HK/news/292775340.md)
generator: "portal-rs"
---

# Tonix Pharmaceuticals Announces Publication in the Peer-Reviewed Journal of Virology Assessing Virulence of the 2022 Outbreak Strain of Mpox in New Animal Models

Information indicates that clade IIb, a strain from the 2022 outbreak, is significantly less virulent compared to clade IIa, a strain from the 2003 outbreak. The data shows that clade IIb is between 100 to 100,000 times less harmful in terms of its virulence when compared to clade IIa. This highlights a notable difference in the virulence levels between these two clades separated by nearly two decades.

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> **Disclaimer: This article is for reference only and does not constitute any investment advice.**