--- title: "US IPO Weekly Recap: CRISPR biotech pops 44% as more names join the IPO pipeline" type: "News" locale: "en" url: "https://longbridge.com/en/news/293800436.md" description: "Scribe Therapeutics priced its IPO at $129 million, surging 44% as it develops CRISPR-based cardiovascular therapies. Meanwhile, defense tech firm Lyntris filed for a $300M offering. The week saw four SPACs join the pipeline, including Bluerock Acquisition II and K2 Capital Acquisition II. Market data shows the Renaissance IPO Index up 16.7% YTD, outperforming the S&P 500." datetime: "2026-07-24T21:34:48.000Z" locales: - [zh-CN](https://longbridge.com/zh-CN/news/293800436.md) - [en](https://longbridge.com/en/news/293800436.md) - [zh-HK](https://longbridge.com/zh-HK/news/293800436.md) generator: "portal-rs" --- # US IPO Weekly Recap: CRISPR biotech pops 44% as more names join the IPO pipeline One IPO priced this past week, joined by four SPACs. Cardiovascular disease biotech **Scribe Therapeutics** (SCTX) upsized and priced at the high end to raise $129 million at a $273 million market cap. Scribe is developing in vivo CRISPR-based therapies, with an initial focus on cardiovascular and metabolic disease. Its lead candidate uses an epigenetic silencing approach to durably lower LDL-C by repressing PCSK9 expression, without permanently altering DNA. It's currently in a first-in-human trial in Australia under TGA clearance, with initial data expected in the first half of 2027. Scribe popped 44%. Two sizable issuers joined the IPO pipeline, led by defense tech firm **Lyntris** (LYNX), which filed for an estimated $300 million offering. | 7 Filings During the Week of July 20th, 2026 | | | | | ----------------------------------------------------------------------------- | ----- | ----------- | ---------------- | | Bluerock Acquisition II (BRRKU) | $150M | SPAC | BTIG | | *Blank check company backed by Bluerock targeting Web3 businesses.* | | | | | K2 Capital Acquisition II (KIIU) | $150M | SPAC | D. Boral Capital | | *Blank check company targeting national defense and critical infrastructure.* | | | | | Lyntris (LYNX) | $300M | Industrials | Evercore ISI | | *Provides defense tech connectivity solutions for military operations.* | | | | | NorthStrive Acquisition I (NOSU.RC) | $100M | SPAC | D. Boral Capital | | *Blank check company targeting manufacturing companies.* | | | | | Pinnacle Acquisition (PNAQ.U) | $200M | SPAC | Santander | | *Blank check company targeting commercial and consumer finance businesses.* | | | | | Gravitics (GVTX) | $125M | Industrials | Lucid Cap. Mkts. | | *Develops large space structures and orbital systems.* | | | | | TCGX Acquisition (TCGX) | $75M | SPAC | Jefferies | | *Blank check company formed by TCGX executives targeting healthcare in Asia.* | | | | **IPO Market Snapshot** The Renaissance IPO Indices are market cap weighted baskets of newly public companies. As of 7/23/2026, the Renaissance IPO Index was up 16.7% year-to-date, while the S&P 500 was up 8.9%. Renaissance Capital's IPO ETF (NYSE: IPO) tracks the index, and top ETF holdings include Astera Labs (ALAB) and CoreWeave (CRWV). The Renaissance International IPO Index was up 38.7% year-to-date, while the ACWX was up 12.9%. 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