---
title: "Weekly Recap | Profusa +14.14%, ISO certification news drives surge"
type: "News"
locale: "en"
url: "https://longbridge.com/en/news/300190547.md"
description: "Profusa (PFSA) rose 14.14% this week to close at $2.18, outperforming the S&P 500 by roughly 12.93 percentage points. The weekly amplitude reached 126.15%, with a sharp rally-and-fade pattern: Monday opened near $1.87, Tuesday and Wednesday ground higher, Thursday surged to $4.18 on ISO 13485 certification news before settling at $3.03, and Friday gave back to $2.18. Average daily volume of 17."
datetime: "2026-09-26T06:52:54.000Z"
locales:
  - [zh-CN](https://longbridge.com/zh-CN/news/300190547.md)
  - [en](https://longbridge.com/en/news/300190547.md)
  - [zh-HK](https://longbridge.com/zh-HK/news/300190547.md)
generator: "portal-rs"
---

# Weekly Recap | Profusa +14.14%, ISO certification news drives surge

## The Week

Profusa (PFSA) rose 14.14% this week to close at $2.18, outperforming the S&P 500 by roughly 12.93 percentage points. The weekly amplitude reached 126.15%, with a sharp rally-and-fade pattern: Monday opened near $1.87, Tuesday and Wednesday ground higher, Thursday surged to $4.18 on ISO 13485 certification news before settling at $3.03, and Friday gave back to $2.18. Average daily volume of 17.55m shares was far above the prior 60-day median of 231k, pointing to a widening divide in positioning.

## Key Events

The company-specific story this week centred on regulatory and product-certification developments. On Monday, shareholders voted to authorise a potential reverse stock split amendment, keeping capital-structure options open. On Thursday, the firm announced significant progress towards CE Mark for its Lumee Oxygen Platform, with ISO 13485 certification expected in early October; the stock briefly gained more than 97% intraday on elevated volume. Friday saw a pullback of over 20%, with heavy turnover signalling disagreement. The name repeatedly appeared on lists of the most active healthcare stocks during pre-market and intraday sessions.

## The Week Ahead

The macro calendar is busy: Dallas Fed manufacturing activity lands on Monday 28 September, followed on Tuesday 29 September by FHFA house prices, Case-Shiller 20-city home prices, JOLTS job openings and consumer confidence. On the company side, valuation remains in negative territory at -0.03x P/E and -0.05x P/B. What to watch: whether ISO 13485 certification is formally secured in early October, and whether further steps on the reverse split are announced.

## In Short

This week’s tension was between regulatory momentum and weak financials inside a highly volatile tape. The positive ISO 13485 decision pushed the Lumee Oxygen Platform’s CE Mark process forward, while turnover rate hit 420.34% and the latest session showed large and medium orders as net buyers, with small orders as net sellers. P/E and P/B are both negative, so the firm is still loss-making. The next test is whether certification arrives on schedule in early October and whether participation holds up after such extreme churn.

*This article is generated by LongbridgeAI from market data, for information only and not investment advice.*

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> **Disclaimer: This article is for reference only and does not constitute any investment advice.**