--- title: "Argenx, Caribou Biosciences And Other Big Stocks Moving Lower In Thursday’s Pre-Market Session" type: "News" locale: "en" url: "https://longbridge.com/en/news/301274698.md" description: "U.S. stock futures fell, with Dow futures down 450 points. Argenx sank 8.7% after halting a Sjögren’s trial for futility. Other stocks sliding include Phreesia (-7.4%), Zevra Therapeutics (-5.8%), and Veeco Instruments (-5.2%). Immunovant dropped 4.8% due to inconclusive trial results. Caribou Biosciences fell 3.7% following an analyst downgrade from Buy to Neutral. Tyler Technologies declined 1.8% after Goldman Sachs downgraded it and cut its price target." datetime: "2026-10-08T12:07:01.000Z" locales: - [zh-CN](https://longbridge.com/zh-CN/news/301274698.md) - [en](https://longbridge.com/en/news/301274698.md) - [zh-HK](https://longbridge.com/zh-HK/news/301274698.md) generator: "portal-rs" --- # Argenx, Caribou Biosciences And Other Big Stocks Moving Lower In Thursday’s Pre-Market Session U.S. stock futures were lower this morning, with the Dow futures falling around 450 points on Thursday. Shares of **argenx SE – ADR** (NASDAQ:ARGX) fell sharply in pre-market trading after the company announced plans to discontinue Phase 3 UNITY study of efgartigimod subcutaneous in adults with moderate-to-severe Sjögren’s disease after IDMC recommended stopping for futility at interim analysis. argenx shares dipped 8.7% to $847.72 in pre-market trading. Here are some other stocks moving lower in pre-market trading. - **Phreesia Inc** (NYSE:PHR) dipped 7.4% to $9.73 in pre-market trading. - **Zevra Therapeutics, Inc.** (NASDAQ:ZVRA) shares tumbled 5.8% to $10.44 in pre-market trading. - **Veeco Instruments Inc**. (NASDAQ:VECO) dipped 5.2% to $50.73 in pre-market trading after falling around 4% on Wednesday. - **PennyMac Mortgage Investment Trust** (NYSE:PMT) declined 5.1% to $7.50 in pre-market trading. - **Immunovant Inc** (NASDAQ:IMVT) fell 4.8% to $30.50 in pre-market trading. Immunovant recently announced topline results from Period 1 of its proof-of-concept trial evaluating IMVT-1402 did not achieve statistical significance on its primary endpoint. - **Cypherpunk Technologies Inc** (NASDAQ:CYPH) declined 4.6% to $2.91 in pre-market trading after falling over 6% on Wednesday. - **STMicroelectronics N.V.** (NYSE:STM) fell 4.5% to $53.62 in pre-market trading after dropping over 4% on Wednesday. - **Dauch Corp** (NYSE:DCH) declined 4.5% to $5.53 in pre-market trading. UBS, on Wednesday, maintained Dauch with a Buy and lowered the price target from $9 to $8. - **WeRide Inc – ADR** (NASDAQ:WRD) fell 4.4% to $4.74 in pre-market trading after declining 3% on Wednesday. - **Aclaris Therapeutics Inc** (NASDAQ:ACRS) declined 4.4% to $3.25 in pre-market trading. - **Xerox Holdings Corporation** (NASDAQ:XRX) declined 4.3% to $2.8797 in pre-market trading after adding around 3% on Wednesday. - **FTAI Aviation Ltd** (NASDAQ:FTAI) fell 4.1% to $167.62 in pre-market trading. FTAI Aviation said it will announce its financial results for the third quarter before the opening bell on Thursday, Oct. 29. - **ArcelorMittal S.A.** (NYSE:MT) slipped 4.1% to $59.77 in pre-market trading after dropping over 4% on Wednesday. - **GDS Holdings Ltd – ADR** (NASDAQ:GDS) declined 4% to $30.38 in pre-market trading.   - **Caribou Biosciences, Inc**. (NASDAQ:CRBU) fell 3.7% to $0.5944 in pre-market trading. HC Wainwright & Co. analyst Robert Burns downgraded Caribou Biosciences from Buy to Neutral. - **Tyler Technologies, Inc.** (NYSE:TYL) fell 1.8% to $326.50 in pre-market trading. Goldman Sachs analyst Adam Hotchkiss downgraded Tyler Technologies from Buy to Neutral and cut the price target from $395 to $345. *Photo via Shutterstock* ### Related Stocks - [ACRS.US](https://longbridge.com/en/quote/ACRS.US.md) - [ARGX.US](https://longbridge.com/en/quote/ARGX.US.md) - [CRBU.US](https://longbridge.com/en/quote/CRBU.US.md) - [CYPH.US](https://longbridge.com/en/quote/CYPH.US.md) - [DSC.US](https://longbridge.com/en/quote/DSC.US.md) - [FTAI.US](https://longbridge.com/en/quote/FTAI.US.md) - [GDS.US](https://longbridge.com/en/quote/GDS.US.md) - [IMVT.US](https://longbridge.com/en/quote/IMVT.US.md) - [LPTX.US](https://longbridge.com/en/quote/LPTX.US.md) - [MT.US](https://longbridge.com/en/quote/MT.US.md) - [PHR.US](https://longbridge.com/en/quote/PHR.US.md) - [PMT.US](https://longbridge.com/en/quote/PMT.US.md) - [STM.US](https://longbridge.com/en/quote/STM.US.md) - [TYL.US](https://longbridge.com/en/quote/TYL.US.md) - [VECO.US](https://longbridge.com/en/quote/VECO.US.md) - [WRD.US](https://longbridge.com/en/quote/WRD.US.md) - [XRX.US](https://longbridge.com/en/quote/XRX.US.md) - [ZVRA.US](https://longbridge.com/en/quote/ZVRA.US.md) - [DDM.US](https://longbridge.com/en/quote/DDM.US.md) - [DIA.US](https://longbridge.com/en/quote/DIA.US.md) - [DXD.US](https://longbridge.com/en/quote/DXD.US.md) - [SDOW.US](https://longbridge.com/en/quote/SDOW.US.md) - [UDOW.US](https://longbridge.com/en/quote/UDOW.US.md) - [.DJI.US](https://longbridge.com/en/quote/.DJI.US.md) ## Related News & Research - [Piper Sandler Reaffirms Their Hold Rating on PennyMac Mortgage (PMT)](https://longbridge.com/en/news/301391953.md) - [BlackRock cools on US stocks, turns bullish on short-dated Treasuries](https://longbridge.com/en/news/301673618.md) - [In the hunt for reverse merger targets, Caribou could be prized game](https://longbridge.com/en/news/301716064.md) - [argenex's (ARGX) Buy Rating Reaffirmed at DZ Bank](https://longbridge.com/en/news/301613360.md) - [Argenx stock sinks as scrapped Vyvgart trial erases $3.5 billion opportunity](https://longbridge.com/en/news/301307663.md) --- > **Disclaimer: This article is for reference only and does not constitute any investment advice.**