---
title: "Johnson & Johnson says long-term data boosts Icotyde for plaque psoriasis"
type: "News"
locale: "en"
url: "https://longbridge.com/en/news/301420344.md"
description: "Johnson & Johnson reported long-term Phase 3 data for Icotyde (icotrokinra) in plaque psoriasis. The ICONIC-LEAD study showed sustained efficacy from week 64 to 112, with over 72% achieving PASI 90 and over 70% reaching clear or almost clear skin. Additionally, more than 44% achieved complete clearance (PASI 100), and improvements in itch were observed."
datetime: "2026-10-09T15:54:38.000Z"
locales:
  - [zh-CN](https://longbridge.com/zh-CN/news/301420344.md)
  - [en](https://longbridge.com/en/news/301420344.md)
  - [zh-HK](https://longbridge.com/zh-HK/news/301420344.md)
generator: "portal-rs"
---

# Johnson & Johnson says long-term data boosts Icotyde for plaque psoriasis

Key points:

-   New phase 3 data found that plaque psoriasis patients treated with Johnson & Johnson's Icotyde (icotrokinra) saw high levels of skin clearance after more than two years of treatment.
-   In the phase 3 placebo-controlled ICONIC-LEAD study, ≥72% of those on the oral IL-23 receptor agonist achieved a Psoriasis Area and Severity Index score (PASI) of 90 and ≥70% achieved clear or almost clear skin (Investigator's Global Assessment \[IGA\] 0/1) from week 64 through week 112.
-   In addition, complete skin clearance continued from week 64 through week 112, as ≥44% of Icotyde reached PASI 100 and ≥46% achieving IGA 0 (clear skin).
-   Improvements in itch were also seen from week 64 through week 112.

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> **Disclaimer: This article is for reference only and does not constitute any investment advice.**