---
title: "Weekly Recap | Upstream Bio -0.72%, most brokers rate it buy"
type: "News"
locale: "en"
url: "https://longbridge.com/en/news/302955596.md"
description: "Upstream Bio (UPB) fell 0.72% this week to close at $2.74, underperforming the S&P 500, which slipped 0.47%. After a pre-market pop of over 11% on Monday, the stock failed to hold the move, trading between $2.75 and $3.09 through Wednesday before closing at $2.99 on Thursday and then dropping nearly 10% intraday on Friday to a range low of $2.695. There was no major catalyst this week; the 14.31% amplitude points to a tape-driven session."
datetime: "2026-10-24T07:12:51.000Z"
locales:
  - [zh-CN](https://longbridge.com/zh-CN/news/302955596.md)
  - [en](https://longbridge.com/en/news/302955596.md)
  - [zh-HK](https://longbridge.com/zh-HK/news/302955596.md)
generator: "portal-rs"
---

# Weekly Recap | Upstream Bio -0.72%, most brokers rate it buy

## The Week

Upstream Bio (UPB) fell 0.72% this week to close at $2.74, underperforming the S&P 500, which slipped 0.47%. After a pre-market pop of over 11% on Monday, the stock failed to hold the move, trading between $2.75 and $3.09 through Wednesday before closing at $2.99 on Thursday and then dropping nearly 10% intraday on Friday to a range low of $2.695. There was no major catalyst this week; the 14.31% amplitude points to a tape-driven session.

## Analyst Ratings

Seven brokers cover the name: four rate it strong buy, one buy, and two hold, with no under or sell ratings. The consensus rating is buy, with a consensus target of $29.83, about 988.8% above spot. Targets range from $9.00 to $75.00, so dispersion is wide. The stock ranks 221st out of 511 biotech names by analyst rating.

## The Week Ahead

Monday brings the US Dallas Fed manufacturing business activity index, followed on Tuesday by durable goods orders, FHFA house prices, the Case Shiller 20-city index, new home sales, the Richmond Fed composite index and consumer confidence. Whether Friday’s intraday record low is absorbed will be an early read on sentiment repair.

*This article is generated by LongbridgeAI from market data, for information only and not investment advice.*

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- [UPB.US](https://longbridge.com/en/quote/UPB.US.md)

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---
> **Disclaimer: This article is for reference only and does not constitute any investment advice.**