--- title: "Nuvalent, Inc. (NUVL.US)" type: "Symbol" locale: "en" url: "https://longbridge.com/en/quote/NUVL.US.md" symbol: "NUVL.US" name: "Nuvalent, Inc." industry: "Biotechnology" datetime: "2026-06-19T09:04:07.276Z" locales: - [en](https://longbridge.com/en/quote/NUVL.US.md) - [zh-CN](https://longbridge.com/zh-CN/quote/NUVL.US.md) - [zh-HK](https://longbridge.com/zh-HK/quote/NUVL.US.md) --- # Nuvalent, Inc. (NUVL.US) ## Company Overview Nuvalent, Inc., a clinical-stage biopharmaceutical company, engages in the development of therapies for patients with cancer. Its lead product candidates are Zidesamtinib (NVL-520), a novel ROS1-selective inhibitor to address the clinical challenges of emergent treatment resistance, central nervous system (CNS)-related adverse events, and brain metastases that may limit the use of ROS1 tyrosine kinase inhibitors (TKIs) for patients with ROS proto-oncogene 1 (ROS1)-positive non-small cell lung cancer (NSCLC) which is under the Phase 2 portion of the ARROS-1 Phase 1/2 clinical trial; Neladalkib (NVL-655), a brain-penetrant ALK-selective inhibitor, to address the clinical challenges of emergent treatment resistance, CNS-related adverse events, and brain metastases that might limit the use of first-, second-, and third-generation ALK inhibitors that is under the Phase 2 portion of the ALKOVE-1 clinical trial; and NVL-330, a brain-penetrant human epidermal growth factor receptor 2 (HER2)-selective inhibitor designed to treat tumors driven by HER2ex20, brain metastases, and avoiding treatment-limiting adverse events including due to off-target inhibition of wild-type EGFR that is in Phase 1a/1b clinical trial. Nuvalent, Inc. has a strategic partnership with Guardant Health, Inc. | Item | Detail | |------|--------| | Industry | Biotechnology | | Exchange | US Market | | Website | [nuvalent.com](https://nuvalent.com) | ## Key Drivers > *AI-analyzed key factors driving this stock's performance* ## Longbridge Financial Score™: > *Longbridge Financial Score™ — Proprietary multi-factor rating model by Longbridge* > Updated: 1970-01-01T00:00:00.000Z **Overall: (0.00)** ## Valuation Analysis | Metric | Current | Industry Ranking | High | Median | Low | |--------|---------|-----------------|------|--------|-----| | PE (TTM) | -21.66 | 504 | - | - | - | | PB | 8.30 | 381 | 9.30 | 6.64 | 5.95 | | Dividend Yield | 0.00% | - | - | - | - | ## Institutional View ### Analyst Rating Distribution > As of 2026-06-10T04:00:00.000Z Total Analysts: **17** | Rating | Count | Percentage | |--------|-------|-----------| | Buy | 1 | 6% | | Hold | 16 | 94% | ### Target Price Forecast | Metric | Price | |--------|-------| | Current Price | 123.43 | | Highest Target | 172.00 | | Lowest Target | 124.00 | ## References - [Company Overview — Profile, executives, shareholders, business breakdown](https://longbridge.com/en/quote/NUVL.US/overview.md) - [Financial Reports — Income, balance sheet, cash flow, dividends](https://longbridge.com/en/quote/NUVL.US/norm.md) - [Related News](https://longbridge.com/en/quote/NUVL.US/news.md) - [Filings — Company announcements and regulatory filings](https://longbridge.com/en/quote/NUVL.US/filings.md) --- > **Disclaimer: This article is for reference only and does not constitute any investment advice.**