ADC Therapeutics Reports 89.8% Response Rate in ZYNLONTA and Glofitamab Phase 1b Trial for r/r DLBCL

Reuters
2025.12.05 22:01
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ADC Therapeutics announced updated results from the LOTIS-7 Phase 1b trial, showing an 89.8% overall response rate and 77.6% complete response rate for ZYNLONTA and glofitamab in r/r DLBCL patients. The combination therapy demonstrated a manageable safety profile, with grade 5 adverse events in 4.1% of patients and cytokine release syndrome in 36.7%. The data was presented by the company and published via EDGAR.