NASDAQ Composite Index has fell 0.14%, with a year-to-date rose 21.9%; S&amp;P 500 has fell 0.35%, with a year-to-date rose 16.4%; Dow Jones Industrial Average has fell 0.45%, with a year-to-date rose 12.2%.Wave Life Sciences(WVE) rose 147.26%, with a trading turnover 2.4 Billion USD, and a year-to-date rose 49.7%.
Structure Therapeutics(GPCR) rose 102.49%, with a trading turnover 1.3 Billion USD, and a year-to-date rose 158%.
Fulcrum Therapeutics(FULC) rose 45.96%, with a trading turnover 343.3 Million USD, and a year-to-date rose 176.4%.<img src="https://pub.pbkrs.com/screenshot/us_increase_top_ten_2025-12-09_en-1765231241226768007.png?x-oss-process=style/lg" original-src="https://pub.pbkrs.com/screenshot/us_increase_top_ten_2025-12-09_en-1765231241226768007.png"/>

GPCR

FULC

KYMR

TERN

CFLT

OCUL

NRIX

WRBY

NUTX

Wave Life Sciences(WVE) rose 147.26%, with a trading turnover 2.4 Billion USD, and a year-to-date rose 49.7%. Structure Therapeutics(GPCR) rose 102.49%, with a trading turnover 1.3 Billion USD, and a year-to-date rose 158%. Fulcrum Therapeutics(FULC) rose 45.96%, with a trading turnover 343.3 Million USD, and a year-to-date rose 176.4%.

Top Gainers & Losers

Wave Life Sciences

Structure Therapeutics

Fulcrum Therapeutics

Kymera Therapeutics

Terns Pharmaceuticals

Confluent

Ocular Therap

Nurix Therapeutics

Warby Parker

Nutex Health

Top 10 US Stock Gainers (12.8)