<div id="readability-page-1"><div>RNS Number : 9099K PureTech Health PLC 10 December 2025 TR-1: Standard form for notification of major holdings1. Issuer DetailsISINGB00BY2Z0H74Issuer NamePURETECH HEALTH PLCUK or Non-UK IssuerUK2. Reason for NotificationAn acquisition or disposal of voting rights3. Details of person subject to the notification obligationNameBaillie Gifford &amp; CoCity of registered office (if applicable)EdinburghCountry of registered office (if applicable)United Kingdom4. Details of the shareholderFull name of shareholder(s) if different from the person(s) subject to the notification obligation, aboveCity of registered office (if applicable)Country of registered office (if applicable)5. Date on which the threshold was crossed or reached08-Dec-20256. Date on which Issuer notified09-Dec-20257. Total positions of person(s) subject to the notification obligation<div><table><tbody><tr><td></td><td>% of voting rights attached to shares (total of 8.A)</td><td>% of voting rights through financial instruments (total of 8.B 1 + 8.B 2)</td><td>Total of both in % (8.A + 8.B)</td><td>Total number of voting rights held in issuer</td></tr><tr><td>Resulting situation on the date on which threshold was crossed or reached</td><td>4.810000</td><td>0.000000</td><td>4.810000</td><td>11625873</td></tr><tr><td>Position of previous notification (if applicable)</td><td>5.280000</td><td>0.000000</td><td>5.280000</td><td>12,529,837</td></tr></tbody></table></div>8. Notified details of the resulting situation on the date on which the threshold was crossed or reached8A. Voting rights attached to shares<div><table><tbody><tr><td>Class/Type of shares ISIN code(if possible)</td><td>Number of direct voting rights (DTR5.1)</td><td>Number of indirect voting rights (DTR5.2.1)</td><td>% of direct voting rights (DTR5.1)</td><td>% of indirect voting rights (DTR5.2.1)</td></tr><tr><td>GB00BY2Z0H74</td><td></td><td>11625873</td><td></td><td>4.810000</td></tr><tr><td>Sub Total 8.A</td><td colspan="2">11625873</td><td colspan="2">4.810000%</td></tr></tbody></table></div>8B1. Financial Instruments according to (DTR5.3.1R.(1) (a))<div><table><tbody><tr><td>Type of financial instrument</td><td>Sub Total 8.B1</td></tr><tr><td>Expiration date</td><td colspan="2"></td></tr><tr><td>Exercise/conversion period</td><td></td></tr><tr><td>Number of voting rights that may be acquired if the instrument is exercised/converted</td><td></td></tr><tr><td>% of voting rights</td></tr></tbody></table></div>8B2. Financial Instruments with similar economic effect according to (DTR5.3.1R.(1) (b))<div><table><tbody><tr><td>Type of financial instrument</td><td>Sub Total 8.B2</td></tr><tr><td>Expiration date</td><td colspan="3"></td></tr><tr><td>Exercise/conversion period</td><td></td></tr><tr><td>Physical or cash settlement</td><td></td></tr><tr><td>Number of voting rights</td></tr><tr><td>% of voting rights</td></tr></tbody></table></div>9. Information in relation to the person subject to the notification obligation2. Full chain of controlled undertakings through which the voting rights and/or the financial instruments are effectively held starting with the ultimate controlling natural person or legal entities (please add additional rows as necessary)<div><table><tbody><tr><td>Ultimate controlling person</td><td>Baillie Gifford &amp; Co</td></tr><tr><td>Name of controlled undertaking</td><td>Baillie Gifford &amp; Co</td></tr><tr><td>% of voting rights if it equals or is higher than the notifiable threshold</td><td></td></tr><tr><td>% of voting rights through financial instruments if it equals or is higher than the notifiable threshold</td><td></td></tr><tr><td>Total of both if it equals or is higher than the notifiable threshold</td><td></td></tr></tbody></table></div>10. In case of proxy votingName of the proxy holderThe number and % of voting rights heldThe date until which the voting rights will be held11. Additional Information12. Date of Completion09-Dec-202513. Place Of CompletionEdinburghThis information is provided by RNS, the news service of the London Stock Exchange. RNS is approved by the Financial Conduct Authority to act as a Primary Information Provider in the United Kingdom. Terms and conditions relating to the use and distribution of this information may apply. For further information, please contact rns@lseg.com or visit www.rns.com.RNS may use your IP address to confirm compliance with the terms and conditions, to analyse how you engage with the information contained in this communication, and to share such analysis on an anonymised basis with others as part of our commercial services. For further information about how RNS and the London Stock Exchange use the personal data you provide us, please see our Privacy Policy. END HOLTLBLTMTBMBBA</div></div>

PRTC

PureTech Health PLC announced a change in major holdings, with Baillie Gifford & Co reducing its voting rights from 5.28% to 4.81%. The notification was triggered by an acquisition or disposal of voting rights, crossing the threshold on December 8, 2025, and reported on December 9, 2025. Baillie Gifford & Co is based in Edinburgh, UK.

REG - PureTech Health PLC - Holding(s) in Company