--- title: "Silence Therapeutics (NASDAQ:SLN) Sets New 52-Week High - Here's Why" type: "News" locale: "en" url: "https://longbridge.com/en/news/293060125.md" description: "Silence Therapeutics (NASDAQ:SLN) stock hit a new 52-week high of $11.19, driven by analyst upgrades including HC Wainwright's $75 target and Cantor Fitzgerald's 'overweight' rating. Despite recent earnings misses and negative margins, institutional ownership remains high at 98.73%, with several hedge funds increasing positions in Q4." datetime: "2026-07-17T16:40:53.000Z" locales: - [zh-CN](https://longbridge.com/zh-CN/news/293060125.md) - [en](https://longbridge.com/en/news/293060125.md) - [zh-HK](https://longbridge.com/zh-HK/news/293060125.md) --- # Silence Therapeutics (NASDAQ:SLN) Sets New 52-Week High - Here's Why Silence Therapeutics PLC Sponsored ADR (NASDAQ:SLN - Get Free Report)'s stock price reached a new 52-week high during trading on Friday . The company traded as high as $11.19 and last traded at $11.1750, with a volume of 28903 shares trading hands. The stock had previously closed at $10.92. Get **Silence Therapeutics** alerts: ## Analysts Set New Price Targets SLN has been the topic of several analyst reports. HC Wainwright reaffirmed a "buy" rating and issued a $75.00 price target on shares of Silence Therapeutics in a report on Wednesday, June 17th. Cantor Fitzgerald began coverage on Silence Therapeutics in a report on Wednesday, June 24th. They set an "overweight" rating for the company. Finally, Weiss Ratings restated a "sell (d-)" rating on shares of Silence Therapeutics in a research note on Tuesday, April 21st. One equities research analyst has rated the stock with a Strong Buy rating, four have assigned a Buy rating and one has issued a Sell rating to the company. According to MarketBeat.com, the company has a consensus rating of "Moderate Buy" and an average target price of $55.00. **Check Out Our Latest Research Report on SLN** ## Silence Therapeutics Trading Down 1.3% The company's 50-day moving average is $7.82 and its 200 day moving average is $6.56. The stock has a market capitalization of $509.06 million, a PE ratio of -6.79 and a beta of 1.38. Silence Therapeutics (NASDAQ:SLN - Get Free Report) last released its earnings results on Friday, May 8th. The company reported ($0.32) earnings per share for the quarter, missing the consensus estimate of ($0.18) by ($0.14). The company had revenue of $0.42 million for the quarter, compared to analysts' expectations of $1.25 million. Silence Therapeutics had a negative return on equity of 105.34% and a negative net margin of 8,943.86%. Sell-side analysts forecast that Silence Therapeutics PLC Sponsored ADR will post -0.83 EPS for the current fiscal year. ## Hedge Funds Weigh In On Silence Therapeutics Several hedge funds have recently made changes to their positions in SLN. XTX Topco Ltd purchased a new position in Silence Therapeutics in the 4th quarter worth $71,000. China Universal Asset Management Co. Ltd. increased its holdings in shares of Silence Therapeutics by 65.9% in the fourth quarter. China Universal Asset Management Co. Ltd. now owns 13,653 shares of the company's stock valued at $83,000 after purchasing an additional 5,421 shares during the period. Citadel Advisors LLC acquired a new position in shares of Silence Therapeutics in the third quarter valued at about $112,000. Massar Capital Management LP purchased a new position in shares of Silence Therapeutics in the second quarter worth about $115,000. Finally, GAMMA Investing LLC raised its stake in shares of Silence Therapeutics by 18.1% in the second quarter. GAMMA Investing LLC now owns 11,063 shares of the company's stock worth $121,000 after purchasing an additional 1,698 shares during the last quarter. 98.73% of the stock is owned by institutional investors and hedge funds. ## Silence Therapeutics Company Profile (Get Free Report) Silence Therapeutics plc is a clinical-stage biotechnology company focused on the discovery and development of ribonucleic acid interference (RNAi) therapeutics. Leveraging its proprietary EnCore lipid nanoparticle delivery platform, the company aims to silence disease-causing genes in the liver and other tissues. Silence's technology is designed to enhance targeted delivery of small interfering RNA (siRNA) molecules, with the goal of achieving durable therapeutic effects and improved safety profiles compared with traditional drug modalities. The company's lead product candidates include SLN360, an siRNA therapeutic designed to reduce lipoprotein(a) levels for cardiovascular risk reduction, and SLN124, aimed at treating hereditary hemochromatosis and beta-thalassemia by modulating iron metabolism. ## Read More - Five stocks we like better than Silence Therapeutics - Aehr Test Systems Stock Soars on Earnings, Eyes Over 150% Revenue Growth - TSMC Just Gave AI Chip Bulls Another Reason to Stay Confident - GE Aerospace Faces a Prove-It Moment in Q2 Earnings - Sandisk: What the Chart Is Trying to Tell Us _This instant news alert was generated by narrative science technology and financial data from MarketBeat in order to provide readers with the fastest reporting and unbiased coverage. Please send any questions or comments about this story to contact@marketbeat.com._ ## Should You Invest $1,000 in Silence Therapeutics Right Now? Before you consider Silence Therapeutics, you'll want to hear this. MarketBeat keeps track of Wall Street's top-rated and best performing research analysts and the stocks they recommend to their clients on a daily basis. MarketBeat has identified the five stocks that top analysts are quietly whispering to their clients to buy now before the broader market catches on... and Silence Therapeutics wasn't on the list. While Silence Therapeutics currently has a Moderate Buy rating among analysts, top-rated analysts believe these five stocks are better buys. 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