--- title: "Pre-market hot trades in US stocks: Applied Optoelectronics fell 3.57% in pre-market; Semtech fell 3.53% in pre-market" type: "News" locale: "en" url: "https://longbridge.com/en/news/293468389.md" description: "Applied Optoelectronics pre-market down 3.57%; Semtech pre-market down 3.53%; InMed Pharmaceuticals pre-market up 105.84%; Inlif pre-market up 72.04%; Core AI pre-market up 51.24%" datetime: "2026-07-22T11:47:49.000Z" locales: - [zh-CN](https://longbridge.com/zh-CN/news/293468389.md) - [en](https://longbridge.com/en/news/293468389.md) - [zh-HK](https://longbridge.com/zh-HK/news/293468389.md) --- # Pre-market hot trades in US stocks: Applied Optoelectronics fell 3.57% in pre-market; Semtech fell 3.53% in pre-market **Popular Pre-Market Trades in US Stocks** Applied Optoelectronics is down 3.57% in pre-market trading. Based on recent key news: 1. On July 20, the Serenity account experienced a 49.4% drawdown, primarily holding small-cap stocks like AAOI, leading to stock price volatility. Odaily reported that Serenity's holdings are concentrated in AI bottlenecks and restricted industries, affecting account performance. 2. On July 20, Applied Optoelectronics had an annualized return of 23.57% over the past decade, performing well in the market. Benzinga pointed out that long-term compound returns significantly enhance investment value. 3. There are no other important news recently. The AI industry is experiencing increased volatility, and investments should be approached with caution. Semtech is down 3.53% in pre-market trading. There is no important news recently; trading is active, and capital flows are evident. Considering sector and industry trends, the stock shows significant volatility, and specific reasons need further observation. no\_news **Top Gainers in Pre-Market Trading in US Stocks** InMed Pharmaceuticals is up 105.84% in pre-market trading. Based on recent news, 1. On July 22, InMed Pharmaceuticals announced significant progress in its new drug development. The company stated in the announcement that its new drug showed significant efficacy in clinical trials, and the market reacted positively, driving the stock price sharply higher. 2. On July 21, analysts raised the target price for InMed Pharmaceuticals, believing that its new drug is expected to bring considerable returns in the coming years. Analysts' optimistic expectations further boosted investor confidence, leading to a rise in stock price. 3. On July 20, InMed Pharmaceuticals announced a partnership agreement with a large pharmaceutical company to jointly develop and promote its new drug. This news was interpreted by the market as a strong guarantee for the company's future growth, pushing the stock price up. The biopharmaceutical industry has performed strongly recently, and investor sentiment is high. Inlif is up 72.04% in pre-market trading, with no important news recently. Trading is active, and capital flows are evident. Considering sector and industry trends, the stock shows significant volatility, and specific reasons need further observation. Core AI is up 51.24% in pre-market trading. Based on recent key news: 1. On July 21, Core AI announced the expansion of its AI strategy, launching multimodal home design and renovation visualization tools, as well as AI-driven residential decision support. This strategic move aims to enhance the company's service capabilities and solidify its position in the industry. This involves significant investment and is expected to expand the company's market coverage. 2. On July 21, Core AI's low price-to-earnings ratio provides some valuation support, but it is not enough to offset financial and trend risks. Nevertheless, the market's increased attention to its AI technology and infrastructure has driven the stock price up On July 21, Core AI described several risk factors in its annual report, including market conditions, customer demand, and supply chain status, which may lead to significant differences between actual results and expectations. Despite these risks, investors remain optimistic about its future growth potential. 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