---
title: "MetaVia (MTVA): Buy Rating Reiterated as DA-1726 Nears Key 4Q26 Data; $20 Price Target Reaffirmed"
type: "News"
locale: "en"
url: "https://longbridge.com/en/news/295394444.md"
description: "H.C. Wainwright analyst Andrew Fein reiterated a Buy rating on MetaVia (MTVA) with a $20 price target, citing the upcoming Q4 2026 data for its obesity drug DA-1726. Positive dose escalation results and emerging metabolic benefits support the view that successful readouts could establish the asset's value and justify Phase 2 trials."
datetime: "2026-08-10T10:45:23.000Z"
locales:
  - [zh-CN](https://longbridge.com/zh-CN/news/295394444.md)
  - [en](https://longbridge.com/en/news/295394444.md)
  - [zh-HK](https://longbridge.com/zh-HK/news/295394444.md)
generator: "portal-rs"
---

# MetaVia (MTVA): Buy Rating Reiterated as DA-1726 Nears Key 4Q26 Data; $20 Price Target Reaffirmed

MetaVia, the Healthcare sector company, was revisited by a Wall Street analyst today. Analyst Andrew Fein from H.C. Wainwright maintained a Buy rating on the stock and has a $20.00 price target.

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Andrew Fein has given his Buy rating due to a combination of factors, primarily centered on the evolving profile of DA-1726 as it advances through clinical development. The successful escalation to the 48 mg and 64 mg dose levels without major tolerability issues, combined with the upcoming 4Q26, 16-week data readout, positions DA-1726 at a potential inflection point where sustained and deepening weight loss, along with incremental efficacy at 64 mg, could materially enhance MetaVia’s value proposition.

Fein’s conviction is further supported by emerging differentiation signals from recent EASL and ADA presentations, which suggest a broader metabolic and hepatic benefit beyond weight reduction alone, including improvements in liver-related measures and dose-proportional exposure at higher doses. With the price target reaffirmed at $20, he views a successful 4Q26 readout—showing clear dose response, manageable gastrointestinal tolerability, and consistent liver signals—as capable of establishing DA-1726 as a distinct obesity-plus-MASH asset and providing a robust foundation for the planned Phase 2 trials, thereby justifying a Buy recommendation on MTVA. 

According to TipRanks, Fein is a 5-star analyst with an average return of 25.5% and a 53.85% success rate. Fein covers the Healthcare sector, focusing on stocks such as Palvella Therapeutics, MetaVia, and Amylyx Pharmaceuticals Inc.

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## Related News & Research

- [MetaVia says all active patients reach highest target doses in DA-1726 obesity Phase 1 Part 3 study](https://longbridge.com/en/news/292199242.md)
- [MetaVia Advances DA-1726 Obesity Trial to Top Doses](https://longbridge.com/en/news/292215429.md)
- [MetaVia presents ADA 2026 data: DA-1726 shows up to 9.1% weight loss; vanoglipel combos show synergistic metabolic and liver benefits](https://longbridge.com/en/news/289060857.md)
- [MetaVia Q2 FY26 net loss widens to $5.3 million](https://longbridge.com/en/news/295139665.md)
- [MetaVia: Buy Rating Reiterated as Synergistic Cardiometabolic Pipeline Supports Unchanged $8 Price Target](https://longbridge.com/en/news/289634793.md)

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> **Disclaimer: This article is for reference only and does not constitute any investment advice.**