---
title: "Bicycle Therapeutics plc (BCYC.US)"
type: "quote"
locale: "en"
url: "https://longbridge.com/en/quote/BCYC.US.md"
symbol: "BCYC.US"
name: "Bicycle Therapeutics plc"
industry: "Biotechnology"
---

# Bicycle Therapeutics plc (BCYC.US)

| Item | Detail |
|------|--------|
| Industry | Biotechnology |
| Location | US Market |
| Website | [www.bicycletherapeutics.com](https://www.bicycletherapeutics.com) |

## Company Profile

Bicycle Therapeutics plc, a clinical-stage pharmaceutical company, develops a class of medicines for diseases that are underserved by existing therapeutics in the United States and the United Kingdom. The company’s products pipeline include zelenectide pevedotin, a bicycle toxin conjugate (BTC), whi...

## Financial Score

> *Longbridge Financial Score™ — Proprietary multi-factor rating model by [Longbridge](https://longbridge.com). This score is independently calculated by Longbridge and is not affiliated with any third-party rating agency.*
> Updated: 2026-02-20T04:30:13.000Z

**Overall: D (0.72)**

**Industry**: Biotechnology

| Metric | Value |
|--------|-------|
| Industry Ranking | 245 / 403 |
| Industry Median | D |
| Industry Average | C |

- **Style**: Value - Stocks where the company's main business is in a mature stage.
- **Scale**: Small - The company's operation has a high degree of growth and volatility, making it easy to achieve high investment returns.

### Score Analysis

**Style Score**: 

#### Growth Score: 

| Indicator | Value | Rating |
|-----------|-------|--------|
| Revenue YoY | -23.20% |  |
| Net Profit YoY | -50.75% |  |

#### Value Score: 

| Indicator | Value | Rating |
|-----------|-------|--------|
| P/B Ratio | 0.62 |  |
| Dividend Ratio | 0.00% |  |


**Size Score**: 

#### Market Cap Score: 

| Indicator | Value | Rating |
|-----------|-------|--------|
| Market Cap | 384.30M |  |

#### Revenue Score: 

| Indicator | Value | Rating |
|-----------|-------|--------|
| Revenue | 28.34M |  |


**Multi Score**: D

#### Profit Score: E

| Indicator | Value | Rating |
|-----------|-------|--------|
| ROE | -34.59% | E |
| Profit Margin | -884.51% | E |
| Gross Margin | -382.46% | E |

#### Growth Score: E

| Indicator | Value | Rating |
|-----------|-------|--------|
| Revenue YoY | -23.20% | E |
| Net Profit YoY | -50.75% | D |
| Total Assets YoY | -23.36% | E |
| Net Assets YoY | -25.58% | E |

#### Cash Score: D

| Indicator | Value | Rating |
|-----------|-------|--------|
| Cash Flow Margin | -11.31% | D |
| OCF YoY | -23.20% | E |

#### Operating Score: E

| Indicator | Value | Rating |
|-----------|-------|--------|
| Turnover | 0.03 | E |

#### Debt Score: A

| Indicator | Value | Rating |
|-----------|-------|--------|
| Gearing Ratio | 19.04% | A |


```chart-data:radar
{
  "title": "Longbridge Financial Score - Bicycle Therapeutics plc",
  "chart_type": "radar",
  "dimensions": [
    {
      "name": "Profit",
      "grade": "E",
      "indicators": [
        {
          "name": "ROE",
          "value": "-34.59%",
          "rating": "E"
        },
        {
          "name": "Profit Margin",
          "value": "-884.51%",
          "rating": "E"
        },
        {
          "name": "Gross Margin",
          "value": "-382.46%",
          "rating": "E"
        }
      ]
    },
    {
      "name": "Growth",
      "grade": "E",
      "indicators": [
        {
          "name": "Revenue YoY",
          "value": "-23.20%",
          "rating": "E"
        },
        {
          "name": "Net Profit YoY",
          "value": "-50.75%",
          "rating": "D"
        },
        {
          "name": "Total Assets YoY",
          "value": "-23.36%",
          "rating": "E"
        },
        {
          "name": "Net Assets YoY",
          "value": "-25.58%",
          "rating": "E"
        }
      ]
    },
    {
      "name": "Cash",
      "grade": "D",
      "indicators": [
        {
          "name": "Cash Flow Margin",
          "value": "-11.31%",
          "rating": "D"
        },
        {
          "name": "OCF YoY",
          "value": "-23.20%",
          "rating": "E"
        }
      ]
    },
    {
      "name": "Operating",
      "grade": "E",
      "indicators": [
        {
          "name": "Turnover",
          "value": "0.03",
          "rating": "E"
        }
      ]
    },
    {
      "name": "Security",
      "grade": "A",
      "indicators": [
        {
          "name": "Gearing Ratio",
          "value": "19.04%",
          "rating": "A"
        }
      ]
    }
  ]
}
```

### Peer Comparison

| Rank | Name | Profit | Growth | Operation | Security | Cash | Rating |
|------|------|--------|--------|-----------|----------|------|--------|
| 01 | Adma Biologics (US.ADMA) | A | A | A | B | B | A |
| 02 | Kiniksa Pharmaceuticals (US.KNSA) | B | A | A | B | A | A |
| 03 | Stoke Therapeutics (US.STOK) | A | A | B | A | B | A |
| 04 | Rigel Pharma (US.RIGL) | A | A | A | C | B | A |
| 05 | OpGen (US.OPGN) | B | A | A | A | B | A |

## Valuation Analysis

| Metric | Current | Industry Ranking | High | Median | Low |
|--------|---------|-----------------|------|--------|-----|
| PE (TTM) | -1.53 | 227/604 | - | - | - |
| PB | 0.62 | 47/604 | 0.82 | 0.76 | 0.72 |
| PS (TTM) | 13.56 | 174/604 | 25.16 | 19.98 | 16.19 |
| Dividend Yield | 0.00% | - | - | - | - |

## Institutional View

### Analyst Rating Distribution

> As of 2026-02-20T05:00:00.000Z

Total Analysts: **13**

| Rating | Count | Percentage |
|--------|-------|-----------|
| Buy | 6 | 46% |
| Overweight | 2 | 15% |
| Hold | 4 | 31% |
| Underweight | 0 | 0% |
| Sell | 0 | 0% |

### Target Price Forecast

| Metric | Price |
|--------|-------|
| Current Price | 5.37 |
| Highest Target | 44.00 |
| Lowest Target | 6.00 |

## References

- [Company Overview](https://longbridge.com/en/quote/BCYC.US/overview.md) - Shareholders, executives, business segments
- [Financials](https://longbridge.com/en/quote/BCYC.US/norm.md) - Income statement, balance sheet, cash flow, distribution plan
- [Topics & Discussions](https://longbridge.com/en/quote/BCYC.US/topics.md) - Community topics and discussions

---

> **Disclaimer**: This article is for reference only and does not constitute any investment advice.