---
title: "德琪医药公布 ATG-022 治疗胃癌 ORR 42.9% 的最新 I/II 期临床数据"
description: "德琪医药公布 ATG-022 治疗晚期或转移性胃癌的最新 I/II 期临床数据，ORR 为 42.9%。该药物是一种抗体偶联药物，针对 CLDN18.2 蛋白，显示出良好的临床疗效。ATG-022 已获得 FDA 的孤儿药资格，适用于胃癌和胰腺癌。"
type: "news"
locale: "zh-CN"
url: "https://longbridge.com/zh-CN/news/225792440.md"
published_at: "2025-01-22T07:25:34.000Z"
---

# 德琪医药公布 ATG-022 治疗胃癌 ORR 42.9% 的最新 I/II 期临床数据

> 德琪医药公布 ATG-022 治疗晚期或转移性胃癌的最新 I/II 期临床数据，ORR 为 42.9%。该药物是一种抗体偶联药物，针对 CLDN18.2 蛋白，显示出良好的临床疗效。ATG-022 已获得 FDA 的孤儿药资格，适用于胃癌和胰腺癌。

德琪医药今日宣布，公司于 2025 年美国临床肿瘤学会胃肠道肿瘤研讨会上公布正在中国和澳大利亚进行中的临床 I/I 期评估 ATG-022 治疗晚期或转移性胃癌患者的 CLINCH 研究的最新数据。ATG-022 是一款被作用于 CLDN18.2 这一紧密连接蛋白的抗体偶联药物，而紧密连接蛋白属于一种细胞黏附分子。美国食品药品监督管理局授予了 ATG-022 两项孤儿药资格认定，分别用于治疗胃癌和胰腺癌。来自正在开展的 CLINCH 研究的数据显示，ATG-022 在不同 CLDN18.2 表达水平的胃癌患者中均显示出良好的临床疗效。目前在 CLDN18.2 不同表达水平的胃癌人群中显示出的疗效提示 ATG-022 有望成为一款极具竞争力的药物。

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