AstraZeneca's CD19×CD3 bispecific therapy for leukemia has been approved for clinical trials in China.

Zhitong
2024.02.29 01:56
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AstraZeneca has been approved to conduct clinical trials for treating leukemia in China. The company's new drug AZD0486 is intended for the treatment of relapsed or refractory B-cell acute lymphoblastic leukemia (r/r B-ALL). AZD0486 is a bispecific T-cell engager protein targeting CD19×CD3, which can guide T cells to tumor cells and kill them. Previously, AstraZeneca acquired TeneoTwo for approximately $1.27 billion, further diversifying its hematology pipeline. AstraZeneca is currently conducting clinical studies on AZD0486 in the United States to evaluate its safety and efficacy in the treatment of B-ALL and B-cell non-Hodgkin's lymphoma (B-NHL).