
HANSOH PHARMA: B7-H3 targeted antibody-drug conjugate HS-20093 received FDA breakthrough therapy designation for relapsed or refractory osteosarcoma in later lines of treatment

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HANSOH PHARMA announced that its B7-H3 targeted antibody-drug conjugate HS-20093 has received Breakthrough Therapy designation from the U.S. FDA for patients with relapsed or refractory osteosarcoma. The drug is covalently linked with a fully human anti-B7-H3 monoclonal antibody and a topoisomerase inhibitor payload, and is currently undergoing multiple clinical studies in China, covering various solid tumors including lung cancer, sarcoma, and head and neck cancer
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