Sanofi Announces Mixed Results from Phase 3 Studies of Itepekimab for COPD Treatment

Reuters
2025.05.30 05:00
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Sanofi SA has reported mixed results from its phase 3 studies of itepekimab for treating chronic obstructive pulmonary disease (COPD) in former smokers. The AERIFY-1 study achieved its primary endpoint with a significant reduction in exacerbations, while the AERIFY-2 study did not meet its primary endpoint despite some earlier benefits. Itepekimab was well tolerated in both studies. Sanofi, in collaboration with Regeneron, is evaluating the data and plans to discuss results with regulatory authorities. The drug is also being assessed for other conditions, including chronic rhinosinusitis and bronchiectasis.