4D Molecular Therapeutics Accelerates Phase 3 Trial for 4D-150 in Wet AMD with Early Initiation of 4FRONT-2

Reuters
2025.08.11 12:01
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4D Molecular Therapeutics Inc. has accelerated its Phase 3 clinical program for 4D-150, a treatment for Wet AMD, with topline data expected in early 2027. The initiation of the 4FRONT-2 trial has also been expedited. This follows positive results from the SPECTRA trial in Diabetic Macular Edema, showing good tolerability and durability. To enhance efficiency, the company has reduced its workforce by 25%.