Eli Lilly's oral weight loss drug phase III data released: average weight loss of 10.5%, will initiate global filing

Zhitong
2025.08.26 12:27
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Eli Lilly announced that its oral weight loss drug orforglipron achieved its primary goal in Phase III clinical trials, with an average weight loss of 10.5% over 72 weeks. The drug will initiate global registration filings, with trials covering over 1,600 obese or overweight patients with type 2 diabetes, achieving all primary and secondary endpoints. The safety profile of orforglipron is consistent with other GLP-1 receptor agonists, but the treatment discontinuation rate is slightly higher. Complete study results will be presented at future medical conferences