Merck & Co. Inc. Initiates Phase 3 HERTHENA-Breast04 Trial for Patritumab Deruxtecan in Treating Advanced HR Positive, HER2 Negative Breast Cancer

Reuters
2025.08.27 11:00
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Merck & Co. Inc. has initiated the HERTHENA-Breast04 phase 3 trial to evaluate the efficacy and safety of patritumab deruxtecan in patients with advanced HR positive, HER2 negative breast cancer. This trial follows promising results from previous studies and aims to provide new treatment options for patients who have not responded to existing therapies. The drug, developed jointly with Daiichi Sankyo, targets HER3 and addresses an unmet medical need in this challenging cancer type. Results from the trial are pending.