Eupraxia Pharmaceuticals Announces Positive 1-Year Clinical Results from RESOLVE Trial for Eosinophilic Esophagitis with EP-104GI

Reuters
2025.09.02 12:15
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Eupraxia Pharmaceuticals Inc. announced positive results from its Phase 1b/2a RESOLVE trial for EP-104GI, a treatment for eosinophilic esophagitis (EoE). Two-thirds of patients in Cohort 5 maintained clinical remission at 12 months post-treatment. All cohorts showed significant improvements in tissue health, with no serious adverse events reported. Plasma levels of fluticasone remained stable, suggesting EP-104GI could enhance current EoE treatments with a potential once-a-year therapy. Further 12-month data from a larger patient group is expected later this year.