<div id="readability-page-1"><p>Polar Asset Management Partners Inc. trimmed its position in shares of  Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX - Free Report) by 62.1% in the first quarter, according to its most recent filing with the Securities and Exchange Commission (SEC). The firm owned 21,594 shares of the pharmaceutical company's stock after selling 35,406 shares during the quarter. Polar Asset Management Partners Inc.'s holdings in Vertex Pharmaceuticals were worth $10,469,000 at the end of the most recent quarter.</p><ul><li>Best Biotech Stocks to Buy in 2025</li></ul><p>Other hedge funds and other institutional investors also recently bought and sold shares of the company. Aries Wealth Management purchased a new position in  Vertex Pharmaceuticals during the 1st quarter valued at about $293,000.  Brighton Jones LLC boosted its holdings in  Vertex Pharmaceuticals by 45.0% during the 1st quarter. Brighton Jones LLC now owns 6,421 shares of the pharmaceutical company's stock valued at $3,113,000 after acquiring an additional 1,994 shares during the period.  GAMMA Investing LLC boosted its holdings in  Vertex Pharmaceuticals by 25.1% during the 1st quarter. GAMMA Investing LLC now owns 5,002 shares of the pharmaceutical company's stock valued at $2,425,000 after acquiring an additional 1,005 shares during the period.  Stanley Laman Group Ltd. purchased a new position in  Vertex Pharmaceuticals during the 1st quarter valued at about $486,000.  Finally, Compagnie Lombard Odier SCmA boosted its stake in shares of  Vertex Pharmaceuticals by 31.4% in the 1st quarter. Compagnie Lombard Odier SCmA now owns 12,565 shares of the pharmaceutical company's stock valued at $6,092,000 after buying an additional 3,000 shares during the period. 90.96% of the stock is currently owned by hedge funds and other institutional investors. </p><div><p><span></span><span>Get <strong>Vertex Pharmaceuticals</strong> alerts:</span></p></div><h2>Vertex Pharmaceuticals Stock Up 0.1%</h2><p>VRTX opened at $396.93 on Friday. The firm has a market cap of $101.77 billion, a price-to-earnings ratio of 28.37 and a beta of 0.44. Vertex Pharmaceuticals Incorporated has a 52 week low of $362.50 and a 52 week high of $519.88. The business's 50 day moving average is $429.40 and its two-hundred day moving average is $456.95. </p><ul><li>MaxCyte: Building the Future of Cell and Gene Therapy Innovation</li></ul><p>Vertex Pharmaceuticals (NASDAQ:VRTX - Get Free Report) last released its quarterly earnings results on Monday, August 4th. The pharmaceutical company reported $4.52 EPS for the quarter, topping the consensus estimate of $4.24 by $0.28. The company had revenue of $2.94 billion for the quarter, compared to analyst estimates of $2.90 billion. Vertex Pharmaceuticals had a return on equity of 23.91% and a net margin of 31.86%.The firm's revenue was up 11.3% compared to the same quarter last year. During the same quarter in the previous year, the company posted ($12.83) earnings per share.  Vertex Pharmaceuticals has set its FY 2025 guidance at  EPS. Equities analysts expect that  Vertex Pharmaceuticals Incorporated will post 15.63 EPS for the current fiscal year. </p><h2>Wall Street Analyst Weigh In</h2><p>VRTX has been the subject of several recent research reports. Stifel Nicolaus decreased their price objective on Vertex Pharmaceuticals from $494.00 to $455.00 and set a &#34;hold&#34; rating for the company in a research note on Tuesday, August 5th. Wall Street Zen cut Vertex Pharmaceuticals from a &#34;strong-buy&#34; rating to a &#34;buy&#34; rating in a research note on Friday, August 22nd. Erste Group Bank cut Vertex Pharmaceuticals from a &#34;strong-buy&#34; rating to a &#34;hold&#34; rating in a research note on Friday, May 23rd. Scotiabank decreased their price objective on Vertex Pharmaceuticals from $442.00 to $438.00 and set a &#34;sector perform&#34; rating for the company in a research note on Tuesday, August 5th. Finally, Guggenheim decreased their price objective on Vertex Pharmaceuticals from $558.00 to $546.00 and set a &#34;buy&#34; rating for the company in a research note on Wednesday, August 6th. One equities research analyst  has rated the stock with a Strong Buy rating, thirteen have assigned  a Buy rating and thirteen have issued  a Hold rating to the company's stock. Based on data from MarketBeat, Vertex Pharmaceuticals  has an average rating of &#34;Moderate Buy&#34; and an average price target of $497.10.</p><ul><li>Vertex's Pain Drug: Big Pharma's Next Major Success?</li></ul><p><b>Get Our Latest Stock Report on Vertex Pharmaceuticals</b></p><h2>Insider Buying and Selling</h2><p>In related news, Director Bruce I. Sachs purchased 5,000 shares of the business's stock in a transaction dated Wednesday, August 6th. The stock was acquired at an average price of $389.68 per share, for a total transaction of $1,948,400.00. Following the completion of the purchase, the director directly owned 45,000 shares of the company's stock, valued at $17,535,600. This trade represents a 12.50% increase in their ownership of the stock. The purchase was disclosed in a filing with the Securities &amp; Exchange Commission, which is accessible through this hyperlink. 0.20% of the stock is currently owned by company insiders. </p><h2>About Vertex Pharmaceuticals</h2> (Free Report)<p>Vertex Pharmaceuticals Incorporated, a biotechnology company, engages in developing and commercializing therapies for treating cystic fibrosis (CF). It markets TRIKAFTA/KAFTRIO for people with CF with at least one F508del mutation for 2 years of age or older; SYMDEKO/SYMKEVI for people with CF for 6 years of age or older; ORKAMBI for CF patients 1 year or older; and KALYDECO for the treatment of patients with 1 year or older who have CF with ivacaftor.</p><h2>Read More</h2><ul><li>Five stocks we like better than Vertex Pharmaceuticals</li><li>How to Use the MarketBeat Excel Dividend Calculator</li><li>Here's What Separates Oklo From the Rest of the Nuclear Startups </li><li>The 3 Best Fintech Stocks to Buy Now</li><li>Why Marvell’s 19% Drop Could Be a Big Buy-the-Dip Opportunity</li><li>Ride Out The Recession With These Dividend Kings </li><li>Daqo New Energy: Solar Monopoly Launches $100M Buyback</li></ul><p><strong>Want to see what other hedge funds are holding VRTX?</strong> Visit HoldingsChannel.com to get the latest 13F filings and insider trades for Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX - Free Report).</p><p><img src="https://imageproxy.pbkrs.com/https://www.marketbeat.com/scripts/SECFilingChart.ashx/query-UHJlZml4PU5BU0RBUSZTeW1ib2w9VlJUWA?x-oss-process=image/auto-orient,1/interlace,1/resize,w_1440,h_1440/quality,q_95/format,jpg" width="650" height="350" original-src="https://imageproxy.pbkrs.com/https://www.marketbeat.com/scripts/SECFilingChart.ashx/query-UHJlZml4PU5BU0RBUSZTeW1ib2w9VlJUWA"/></p><p><em>This instant news alert was generated by narrative science technology and financial data from MarketBeat in order to provide readers with the fastest and most accurate reporting. This story was reviewed by MarketBeat's editorial team prior to publication. Please send any questions or comments about this story to contact@marketbeat.com.</em></p><h2>Should You Invest $1,000 in Vertex Pharmaceuticals Right Now?</h2><p>Before you consider Vertex Pharmaceuticals, you'll want to hear this.</p><p>MarketBeat keeps track of Wall Street's top-rated and best performing research analysts and the stocks they recommend to their clients on a daily basis. MarketBeat has identified the five stocks that top analysts are quietly whispering to their clients to buy now before the broader market catches on... and Vertex Pharmaceuticals wasn't on the list.</p><p>While Vertex Pharmaceuticals currently has a Moderate Buy rating among analysts, top-rated analysts believe these five stocks are better buys.</p><p>View The Five Stocks Here</p>                  </div>

VRTX

<p>Polar Asset Management Partners Inc. reduced its stake in Vertex Pharmaceuticals (NASDAQ:VRTX) by 62.1% in Q1, now holding 21,594 shares valued at $10.47 million. Other institutional investors also adjusted their positions, with notable increases from Brighton Jones LLC and GAMMA Investing LLC. Vertex's stock opened at $396.93, with a market cap of $101.77 billion. The company reported a Q2 EPS of $4.52, exceeding estimates, and has set a FY 2025 EPS guidance. Analysts have mixed ratings, with an average target of $497.10 for the stock.</p>

Polar Asset Management Partners Inc. Lowers Stock Holdings in Vertex Pharmaceuticals Incorporated $VRTX