
Alnylam Pharmaceuticals Announces Positive HELIOS-B Phase 3 Results for AMVUTTRA® (Vutrisiran), Showing Reduced GI Events in ATTR-CM Patients

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Alnylam Pharmaceuticals Inc. announced positive results from the HELIOS-B Phase 3 study of AMVUTTRA® (vutrisiran), showing a 37-49% reduction in gastrointestinal adverse events compared to placebo in ATTR-CM patients. The findings, presented at the HFSA Annual Scientific Meeting 2025, support the safety and efficacy of vutrisiran and its recent approvals in multiple regions, including the US and EU.
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