NASDAQ Composite Index has rose 0.42%, with a year-to-date rose 17.8%; S&amp;P 500 has rose 0.34%, with a year-to-date rose 14.1%; Dow Jones Industrial Average has rose 0.09%, with a year-to-date rose 9.2%.Astrazeneca(AZN) rose 9.96%, with a trading turnover 1.2 Billion USD, and a year-to-date rose 31.5%.
Thermo Fisher Scentific(TMO) rose 9.42%, with a trading turnover 3.2 Billion USD, and a year-to-date rose 2.3%.
Mercadolibre(MELI) fell 6.85%, with a trading turnover 2.6 Billion USD, and a year-to-date rose 28%.
Wells Fargo(WFC) fell 3.52%, with a trading turnover 1.4 Billion USD, and a year-to-date rose 17%.<img src="https://pub.pbkrs.com/screenshot/us_company_top_five_2025-10-02_en-1759356040943540288.png?x-oss-process=style/lg" original-src="https://pub.pbkrs.com/screenshot/us_company_top_five_2025-10-02_en-1759356040943540288.png"/>

MELI

SCHW

HOOD

Astrazeneca(AZN) rose 9.96%, with a trading turnover 1.2 Billion USD, and a year-to-date rose 31.5%. Thermo Fisher Scentific(TMO) rose 9.42%, with a trading turnover 3.2 Billion USD, and a year-to-date rose 2.3%. Mercadolibre(MELI) fell 6.85%, with a trading turnover 2.6 Billion USD, and a year-to-date rose 28%. Wells Fargo(WFC) fell 3.52%, with a trading turnover 1.4 Billion USD, and a year-to-date rose 17%.

- The Nasdaq Composite Index rose by 0.42%, with a year-to-date increase of 17.8%.  
- The S&P 500 Index increased by 0.34%, accumulating a 14.1% rise this year, while the Dow Jones Index saw a 0.09% gain, totaling a 9.2% increase for the year.  
- Notable stock movements include AstraZeneca rising by 9.96% and Wells Fargo declining by 3.52%, with respective year-to-date changes of 31.5% and 17%.  

Top 5 US Stock Gainers/Losers (>100B) (10.1)