<div id="readability-page-1"> <time datetime="2025-10-03T15:53:00.000Z"> 10/03/2025 - 11:53 AM </time> Smith+Nephew (NYSE:SNN; LSE:SN), the global medical technology business, is pleased to announce exciting new data from Professor Amit Gefen and his research group published in the International Wound Journal,1 demonstrating the pressure injury prevention mechanism of action of ALLEVYN COMPLETE CARE Foam Dressing and its ability to absorb and dissipate friction and shear forces. Pressure injuries are localized damage to the skin or underlying tissue, resulting from prolonged exposure to pressure in combination with shear forces.2 This landmark study demonstrates that the new ALLEVYN COMPLETE CARE Foam Dressing absorbs 93% of mechanical energy into its internal layers. The study shows that the dressing absorbs and dissipates shear forces internally and layer-to-layer frictional sliding within the dressing. This mechanism of action can significantly help reduce the harmful stress concentrations that are known to cause pressure injuries, a clinical burden which costs the US healthcare system over $26.8bn every year.3 <img height="269" src="https://imageproxy.pbkrs.com/https://ml-eu.globenewswire.com/Resource/Download/674c39be-7cd5-465d-80cf-75f3ec8160bb/allevyn-complete-care-family-shot-rgb-large-white-no-logos.jpg?x-oss-process=image/auto-orient,1/interlace,1/resize,w_1440,h_1440/quality,q_95/format,jpg" width="456" original-src="https://imageproxy.pbkrs.com/https://ml-eu.globenewswire.com/Resource/Download/674c39be-7cd5-465d-80cf-75f3ec8160bb/allevyn-complete-care-family-shot-rgb-large-white-no-logos.jpg"/> By using both Frictional Energy Absorber Effectiveness (FEAE) and Finite Element Modelling (FEM), the results confirmed the mechanism of action of ALLEVYN COMPLETE CARE Dressing in mitigating mechanical loading and protecting underlying soft tissue. “These findings represent a significant step forward in pressure injury prevention,” said Amit Gefen, Professor of Biomedical Engineering at Tel Aviv University. “ALLEVYN COMPLETE CARE Dressing's advanced biomechanical performance dissipates potentially harmful shear forces, which can help protect patients from factors that contribute to pressure injuries.” ''Pressure injuries are a complex and costly challenge, placing a heavy burden on both patients and healthcare systems,&#34; said Rohit Kashyap, President, Advanced Wound Management at Smith+Nephew. “This publication showcases the distinct mechanism of action of ALLEVYN COMPLETE CARE Foam Dressing and its ability to dissipate shear forces, helping to protect more patients from the harm of pressure injuries.” ALLEVYN COMPLETE CARE Dressing will be launched into the US advanced wound care market later in the year, followed by subsequent markets throughout 2026, and is indicated for the management of a range of wounds and pressure injury prevention. Building on the successful mechanism of action principles originally established by ALLEVYN LIFE Dressing,4 the new ALLEVYN COMPLETE CARE Foam Dressing demonstrated an increased Frictional Energy Absorber Effectiveness, up from 30-45% to 93%. To read the full publication, please click here. References <ol><li>Orlova D, Orlov A, Gefen A. The Protective Efficacy of a New Soft Silicone Multi-Layer Dressing in Reducing the Heel Pressure Ulcer Risk. Int Wound J. 2025;22(10):e70764.</li><li>National Pressure Injury Advisory Panel, European Pressure Ulcer Advisory Panel and Pan Pacific Pressure Injury Alliance. Pressure Ulcers/Injuries: Definition and Etiology. In: Prevention and Treatment of Pressure Ulcers/Injuries: Clinical Practice Guideline. The International Guideline: Fourth Edition. Emily Haesler (Ed.). 2025. [cited: 3rd October 2025]. Available from: https://internationalguideline.com.</li></ol> <ol><li value="3">Padula W V., &amp; Delarmente, B. A. (2019). The national cost of hospital-acquired pressure injuries in the United States. Wound Repair and Regeneration, 27(3), 329–335 WV, Delarmente BA. The national cost of hospital-acquired pressure injuries in the United States. Int Wound J. 2019;16(3):634-640..</li></ol> <ol type="1"><li value="4">Marché C, Creehan S, Gefen A. The frictional energy absorber effectiveness and its impact on the pressure ulcer prevention performance of multilayer dressings. Int Wound J. 2024;21(4):e14871.</li></ol> - Ends – Enquiries: <table><tbody><tr><td>Media</td><td></td></tr><tr><td>Frida Wilhelmsson</td><td>+46 738499429 </td></tr><tr><td>Smith+Nephew</td><td></td></tr></tbody></table> About Smith+Nephew Smith+Nephew is a portfolio medical technology business focused on the repair, regeneration and replacement of soft and hard tissue. We exist to restore people’s bodies and their self-belief by using technology to take the limits off living. We call this purpose ‘Life Unlimited’. Our 17,000 employees deliver this mission every day, making a difference to patients’ lives through the excellence of our product portfolio, and the invention and application of new technologies across our three global business units of Orthopaedics, Sports Medicine &amp; ENT and Advanced Wound Management. Founded in Hull, UK, in 1856, we now operate in around 100 countries and generated annual sales of $5.8 billion in 2024. Smith+Nephew is a constituent of the FTSE100 (LSE:SN, NYSE:SNN). The terms ‘Group’ and ‘Smith+Nephew’ are used to refer to Smith &amp; Nephew plc and its consolidated subsidiaries, unless the context requires otherwise. For more information about Smith+Nephew, please visit www.smith-nephew.com and follow us on X, LinkedIn, Instagram or Facebook. Forward-looking Statements This document may contain forward-looking statements that may or may not prove accurate. For example, statements regarding expected revenue growth and trading profit margins, market trends and our product pipeline are forward-looking statements. Phrases such as &#34;aim&#34;, &#34;plan&#34;, &#34;intend&#34;, &#34;anticipate&#34;, &#34;well-placed&#34;, &#34;believe&#34;, &#34;estimate&#34;, &#34;expect&#34;, &#34;target&#34;, &#34;consider&#34; and similar expressions are generally intended to identify forward-looking statements. Forward-looking statements involve known and unknown risks, uncertainties and other important factors that could cause actual results to differ materially from what is expressed or implied by the statements. For Smith+Nephew, these factors include: conflicts in Europe and the Middle East, economic and financial conditions in the markets we serve, especially those affecting healthcare providers, payers and customers; price levels for established and innovative medical devices; developments in medical technology; regulatory approvals, reimbursement decisions or other government actions; product defects or recalls or other problems with quality management systems or failure to comply with related regulations; litigation relating to patent or other claims; legal and financial compliance risks and related investigative, remedial or enforcement actions; disruption to our supply chain or operations or those of our suppliers; competition for qualified personnel; strategic actions, including acquisitions and disposals, our success in performing due diligence, valuing and integrating acquired businesses; disruption that may result from transactions or other changes we make in our business plans or organisation to adapt to market developments; relationships with healthcare professionals; reliance on information technology and cybersecurity; disruptions due to natural disasters, weather and climate change related events; changes in customer and other stakeholder sustainability expectations; changes in taxation regulations; effects of foreign exchange volatility; and numerous other matters that affect us or our markets, including those of a political, economic, business, competitive or reputational nature. 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Smith+Nephew has announced new scientific data supporting its ALLEVYN COMPLETE CARE Foam Dressing for pressure injury prevention. Research published in the International Wound Journal shows that the dressing absorbs 93% of mechanical energy, effectively dissipating friction and shear forces that contribute to pressure injuries. This innovation aims to reduce the clinical burden of pressure injuries, which cost the US healthcare system over $26.8 billion annually. The dressing will launch in the US market later this year, with further expansion planned for 2026.

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Smith+Nephew announce latest scientific data supporting new ALLEVYN™ COMPLETE CARE 5-Layer Foam Dressing for pressure injury prevention | SNN Stock News