<div id="readability-page-1"><div>RNS Number : 3490D Trium Capital LLP 14 October 2025 FORM 8.3IRISH TAKEOVER PANELOPENING POSITION DISCLOSURE/DEALING DISCLOSURE UNDER RULE 8.3 OF THE IRISH TAKEOVER PANEL ACT, 1997, TAKEOVERRULES, 2022 BY PERSONS WITH INTERESTS IN RELEVANT SECURITIES REPRESENTING 1% OR MORE1. KEY INFORMATION<div><table><tbody><tr><td>(a) Full name of discloser</td><td>Trium Capital LLP</td></tr><tr><td>(b) Owner or controller of interests and short positions disclosed, if different from 1(a)The naming of nominee or vehicle companies is insufficient. For a trust, the trustee(s), settlor and beneficiaries must be named.</td><td></td></tr><tr><td>(c) Name of offeror/offeree in relation to whose relevant securities this form relatesUse a separate form for each offeror/offeree</td><td>MURAL ONCOLOGY PLC</td></tr><tr><td>(d) If an exempt fund manager connected with an offeror/offeree, state this and specify identity of offeror/offeree (Note 1)</td><td></td></tr><tr><td>(e) Date position held/dealing undertakenFor an opening position disclosure, state the latest practicable date prior to the disclosure</td><td>13/10/2025</td></tr><tr><td>(f) In addition to the company in 1(c) above, is the discloser also making disclosures in respect of any other party to the offer?If it is a cash offer or possible cash offer, state &#34;N/A&#34;</td><td> N/A:</td></tr></tbody></table></div>2. INTERESTS AND SHORT POSITIONSIf there are interests and short positions to disclose in more than one class of relevant securities of the offeror or offeree named in 1(c), copy table 2 for each additional class of relevant security.Interests and short positions in the relevant securities of the offeror or offeree to which the disclosure relates following the dealing (if any)(Note 2)<div><table><tbody><tr><td>Class of relevant security (Note 3)</td><td colspan="4">USD 0.01</td></tr><tr><td rowspan="2"></td><td colspan="2">Interests</td><td colspan="2">Short positions</td></tr><tr><td>Number</td><td>%</td><td>Number</td><td>%</td></tr><tr><td>(1) Relevant securities owned and/or controlled</td><td>1,849,026</td><td>10.71</td><td></td><td></td></tr><tr><td>(2) Cash-settled derivatives</td><td>54,256</td><td>0.31</td><td></td><td></td></tr><tr><td>(3) Stock-settled derivatives (including options) and agreements to purchase/ sell</td><td></td><td></td><td></td><td></td></tr><tr><td>Total</td><td>1,903,082</td><td>11.02</td><td></td><td></td></tr></tbody></table></div>All interests and all short positions should be disclosed.Details of options including rights to subscribe for new securities and any open stock-settled derivative positions (including traded options), or agreements to purchase or sell relevant securities, should be given on a Supplemental Form 8.3. DEALINGS (IF ANY) BY THE PERSON MAKING THE DISCLOSURE (Note 4)Where there have been dealings in more than one class of relevant securities of the offeror or offeree named in 1(c), copy table 3(a), (b), (c) or (d) (as appropriate) for each additional class of relevant security dealt in.The currency of all prices and other monetary amounts should be stated.(a) Purchases and sales<div><table><tbody><tr><td>Class of relevantsecurity</td><td> USD 0.01</td></tr><tr><td>Purchase/sale</td><td>Purchase</td></tr><tr><td>Number ofsecurities</td><td>200</td></tr><tr><td>Price per unit (Note 5)</td><td>USD 2.07</td></tr></tbody></table></div>(b) Cash-settled derivative transactions(c) Stock-settled derivative transactions (including options)(i) Writing, selling, purchasing or varying<ul><li>Class of relevant security</li><li>Product description e.g. call option</li><li>Writing, purchasing, selling, varying etc.</li><li>Number of securities to which option relates (Note 6)</li><li>Exerciseprice per unit</li><li>Type e.g. American, Europeanetc.</li><li>Expiry date</li><li>Option moneypaid/ received per unit</li></ul>(ii) Exercise<ul><li>Class of relevant security</li><li>Product description e.g. call option</li><li>Exercising/ exercised against</li><li>Number of securities</li><li>Exercise price per unit (Note 5)</li></ul>(d) Other dealings (including transactions in respect of new securities) (Note 3)<ul><li>Class of relevant security</li><li>Nature of dealing e.g. subscription, conversion, exercise</li><li>Details</li><li>Price per unit (if applicable) (Note 5)</li></ul>4. OTHER INFORMATION(a) Indemnity and other dealing arrangements<ul><li>Details of any indemnity or option arrangement, or any agreement or understanding, formal or informal, relating to relevant securities which may be an inducement to deal or refrain from dealing entered into by the person making the disclosure and any party to the offer or any person acting in concert with a party to the offer.Irrevocable commitments and letters of intent should not be included. If there are no such agreements, arrangements or understandings, state &#34;none&#34;</li><li>NONE</li></ul>(b) Agreements, arrangements or understandings relating to options or derivatives<ul><li>Full details of any agreement, arrangement or understanding between the person disclosing and any other person relating to the voting rights of any relevant securities under any option referred to on this form or relating to the voting rights or future acquisition or disposal of any relevant securities to which any derivative referred to on this form is referenced. If none, this should be stated.</li><li>NONE</li></ul>(c) Attachments<ul><li>Is a Supplemental Form 8 attached?</li><li>NO</li></ul><div><table><tbody><tr><td>Date of disclosure</td><td>14/10/2025</td></tr><tr><td>Contact name</td><td>Andrew Crick</td></tr><tr><td>Telephone number</td><td>+44 (0) 20 7073 9269</td></tr></tbody></table></div>Public disclosures under Rule 8.3 of the Rules must be made to a Regulatory Information Service.This information is provided by RNS, the news service of the London Stock Exchange. RNS is approved by the Financial Conduct Authority to act as a Primary Information Provider in the United Kingdom. Terms and conditions relating to the use and distribution of this information may apply. For further information, please contact rns@lseg.com or visit www.rns.com.RNS may use your IP address to confirm compliance with the terms and conditions, to analyse how you engage with the information contained in this communication, and to share such analysis on an anonymised basis with others as part of our commercial services. For further information about how RNS and the London Stock Exchange use the personal data you provide us, please see our Privacy Policy. END ITPBSBDGUDBDGUS</div></div>

MURA

Trium Capital LLP disclosed its position in Mural Oncology PLC under Rule 8.3 of the Irish Takeover Panel Act. As of October 13, 2025, Trium holds 1,849,026 relevant securities (10.71%) and cash-settled derivatives of 54,256 (0.31%), totaling 1,903,082 (11.02%). The disclosure includes a purchase of 200 securities at USD 2.07 each. No other agreements or arrangements were reported. The disclosure was made on October 14, 2025, by Andrew Crick, with contact details provided for further inquiries.

REG - Trium Capital LLP Mural Oncology PLC - Form 8.3 - MURAL ONCOLOGY PLC