<div id="readability-page-1"><div><div>U.S. stocks traded lower midway through trading, with the Dow Jones index falling more than 100 points on Thursday.The Dow traded down 0.30% to 46,113.98 while the NASDAQ slipped 0.21% to 22,622.73. The S&amp;P 500 also fell, dropping, 0.34% to 6,648.52.Check This Out: Top 2 Health Care Stocks That May Keep You Up At Night This Month<div>Leading and Lagging SectorsReal estate shares jumped by 0.5% on Thursday.</div>In trading on Thursday, financial stocks fell by 1.5%.Top HeadlineU.S. crude oil inventories surged by 3.524 million barrels in the week ending Oct. 10, compared to market estimates of a 0.12-million gain.Equities Trading UP <ul> <li>Praxis Precision Medicines Inc (NASDAQ:PRAX) shares shot up 208% to $176.74. The clinical-stage biopharmaceutical company released topline results for the Phase 3 Essential3 program of ulixacaltamide in essential tremor (ET).</li> <li>Shares of J.B. Hunt Transport Services, Inc. (NASDAQ:JBHT) got a boost, surging 20% to $166.65 after the company reported better-than-expected quarterly financial results. Also, multiple firms raised their respective price targets on the stock.</li> <li>Mira Pharmaceuticals Inc (NASDAQ:MIRA) shares were also up, gaining 57% to $2.07 after the company announced new preclinical data for Mira-55.</li> </ul>Equities Trading DOWN<ul> <li>UTime Ltd (NASDAQ:WTO) shares dropped 88% to $0.1496 after the company reported pricing of $25 million registered direct offering.</li> <li>Shares of Theriva Biologics Inc (NYSE:TOVX) were down 46% to $0.4495 after the company announced a $4 million warrant inducement agreement for the immediate exercise of warrants to purchase up to 7,360,460 of common stock at a reduced exercise price of $0.54 per share.</li> <li>Hyperfine Inc (NASDAQ:HYPR) was down, falling 41% to $1.3050 after the company announced the pricing of its $17.5 million public offering of 14 million shares at a price of $1.25 per share.</li> </ul><div>CommoditiesIn commodity news, oil traded up 0.1% to $58.32 while gold traded up 2.3% at $4,296.60.</div>Silver traded up 4.2% to $53.515 on Thursday, while copper fell 0.1% to $5.0115.Euro zoneEuropean shares were higher today. The eurozone's STOXX 600 rose 0.69%, while Spain's IBEX 35 Index rose 0.48%. London's FTSE 100 rose 0.12%, Germany's DAX 40 gained 0.38% and France's CAC 40 surged 1.38% during the session.Asia Pacific MarketsAsian markets closed mostly higher on Thursday, with Japan's Nikkei 225 surging 1.27%, Hong Kong's Hang Seng index falling 0.09%, China's Shanghai Composite rising 0.10% and India's BSE Sensex rising 1.04%.Economics<ul> <li>The Philadelphia Fed Manufacturing Index declined to a six-month low level of -12.8 in October from 23.2 in the previous month and missing market estimates of 10.</li> <li>U.S. crude oil inventories surged by 3.524 million barrels in the week ending Oct. 10, compared to market estimates of a 0.12-million gain.</li> <li>U.S. natural-gas stocks rose by 80 billion cubic feet in the week ending Oct. 10.</li> </ul>Now Read This: <ul> <li>How To Earn $500 A Month From Ally Financial Stock Ahead Of Q3 Earnings</li> </ul>Photo via Shutterstock</div></div></div>

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U.S. stocks fell, with the Dow Jones down over 100 points, while crude oil inventories surged by 3.524 million barrels, exceeding expectations. Praxis Precision Medicines saw a 208% increase in shares after positive trial results, while J.B. Hunt's shares rose 20% following strong quarterly results. Conversely, UTime Ltd shares plummeted 88% after a direct offering announcement. The Philadelphia Fed Manufacturing Index dropped to -12.8, indicating a decline in manufacturing activity. European and Asian markets showed mixed performance, with some indices rising and others falling.

- U.S. stocks declined, with the Dow Jones falling over 100 points, while the S&P 500 and NASDAQ also experienced losses.  
- Real estate shares increased by 0.5%, but financial stocks dropped by 1.5%, and U.S. crude oil inventories surged by 3.524 million barrels, exceeding market expectations.  
- European and Asian markets showed mixed results, with the Philadelphia Fed Manufacturing Index declining to a six-month low of -12.8 in October.

Dow Dips Over 100 Points; US Crude Oil Inventories Surge