NASDAQ Composite Index has fell 0.93%, with a year-to-date rose 17.8%; S&amp;P 500 has fell 0.53%, with a year-to-date rose 13.9%; Dow Jones Industrial Average has fell 0.71%, with a year-to-date rose 9.5%.Intuitive Surgical(ISRG) rose 13.89%, with a trading turnover 4.4 Billion USD, and a year-to-date rose 1%.
Boston Scientific(BSX) rose 3.95%, with a trading turnover 1.8 Billion USD, and a year-to-date rose 16.3%.
Biodexa Pharmaceuticals(BDRX) fell 10.6%, with a trading turnover 156.1 Thousand USD, and a year-to-date fell 83.3%.
Netflix(NFLX) fell 10.07%, with a trading turnover 16.6 Billion USD, and a year-to-date rose 25.2%.<img src="https://pub.pbkrs.com/screenshot/us_company_top_five_2025-10-23_en-1761170430909527074.png?x-oss-process=style/lg" original-src="https://pub.pbkrs.com/screenshot/us_company_top_five_2025-10-23_en-1761170430909527074.png"/>

ISRG

BDRX

NFLX

DASH

HOOD

Intuitive Surgical(ISRG) rose 13.89%, with a trading turnover 4.4 Billion USD, and a year-to-date rose 1%. Boston Scientific(BSX) rose 3.95%, with a trading turnover 1.8 Billion USD, and a year-to-date rose 16.3%. Biodexa Pharmaceuticals(BDRX) fell 10.6%, with a trading turnover 156.1 Thousand USD, and a year-to-date fell 83.3%. Netflix(NFLX) fell 10.07%, with a trading turnover 16.6 Billion USD, and a year-to-date rose 25.2%.

- The Nasdaq Composite Index fell by 0.93%, with a year-to-date increase of 17.8%.  
- The S&P 500 Index decreased by 0.53%, accumulating a 13.9% rise this year, while the Dow Jones Index dropped by 0.71% with a 9.5% year-to-date gain.  
- Notable stock movements include Intuitive Surgical rising by 13.89% and Netflix declining by 10.07%.

Top 5 US Stock Gainers/Losers (>100B) (10.22)