BUZZ-Ventyx jumps as oral drug reduces heart disease risk markers in mid-stage trial

Reuters
2025.10.23 09:57
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Shares of Ventyx Biosciences surged 70% to $6.58 in premarket trading after the company announced that its oral drug VTX3232 significantly reduced key inflammation markers associated with heart disease in a mid-stage trial. The drug lowered hsCRP levels by approximately 80% within the first week and also reduced IL-6 levels below the cardiovascular risk threshold. Additionally, a combination with Novo Nordisk’s semaglutide further decreased inflammation markers, although it did not enhance weight loss. Year-to-date, VTYX shares are up about 76%.