Boundless Bio Unveils New Therapies Targeting ecDNA-Driven Cancer

Reuters
2025.11.10 18:51
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Boundless Bio Inc. has introduced new ecDNA-directed therapies (ecDTx) aimed at treating oncogene amplified cancers, which lack effective existing treatments. Their clinical-stage candidates include BBI-355 and BBI-825, currently in the POTENTIATE trial, and BBI-940, set to enter trials in 2026. With 25% of cancer patients having amplified oncogenes, this approach addresses a significant medical need. The full presentation is available via a provided link.