<div id="readability-page-1"><div><p>Disc Medicine (IRON) is making waves with two major updates. The company has launched a Phase 1b trial for its investigational therapy in sickle cell disease, and the FDA has granted priority review to its new drug application for bitopertin.</p> <p>See our latest analysis for Disc Medicine.</p> <p>Disc Medicine’s clinical and regulatory momentum appears to be fueling strong investor interest, with the stock delivering a robust 51.3% total shareholder return over the past year and a 50% share price return in the last 90 days alone. Short-term momentum has clearly picked up, and recent news around trial progress and priority review adds to the optimism about long-term growth prospects.</p> <p>If the buzz around Disc Medicine’s new trial and FDA review has you watching the sector closely, now is a great opportunity to discover other healthcare stocks making headlines by exploring See the full list for free.</p> <p>With Disc Medicine’s shares surging on clinical milestones and regulatory catalysts, the key question for investors is whether these gains leave room for more upside or if the market is already factoring in future growth.</p> <h2>Price-to-Book Ratio of 5.9x: Is it justified?</h2> <p>Disc Medicine currently trades at a price-to-book (P/B) ratio of 5.9x, using the last close price of $89.95. This level suggests investors are assigning a premium to Disc Medicine’s net asset value, compared both to the sector and to its closest peers.</p> <p>The price-to-book ratio reflects what investors are willing to pay for each dollar of company assets. For biotech firms like Disc Medicine, this ratio can be especially significant because it incorporates market hopes for the company’s future scientific and commercial breakthroughs beyond its current book value.</p> <p>At 5.9x, Disc Medicine’s P/B ratio is higher than the US Biotechs industry average of 2.5x. However, when comparing against its peer average of 102x, the company appears relatively attractively valued within its group. If the market were to shift closer to peer levels, significant upside could emerge. Relative to the industry average, though, the stock looks expensive on this metric.</p> <p>See what the numbers say about this price — find out in our valuation breakdown.</p> <p><strong>Result: Price-to-Book of 5.9x (OVERVALUED compared to industry average, UNDERVALUED compared to peer average)</strong></p> <p>However, risks remain if clinical results disappoint or if competitive developments emerge. Either scenario could quickly shift sentiment and current momentum around Disc Medicine.</p> <p>Find out about the key risks to this Disc Medicine narrative.</p> <h2>Another View: Discounted Cash Flow Perspective</h2> <p>Looking at Disc Medicine through our DCF model offers a different picture from the price-to-book valuation. The SWS DCF model estimates a fair value of $100.52, which is around 10.5% above the current share price. This suggests Disc Medicine could be undervalued based on the company's expected future cash flows. The question remains whether this more optimistic view outweighs the risks implied by standard multiples.</p> <p>Look into how the SWS DCF model arrives at its fair value.</p> <figure><img height="476" src="https://imageproxy.pbkrs.com/https://images.simplywall.st/company/2bb88255-5b25-4ce7-bb16-867fff68cc39/chart/dcf?x-oss-process=image/auto-orient,1/interlace,1/resize,w_1440,h_1440/quality,q_95/format,jpg" width="746" original-src="https://imageproxy.pbkrs.com/https://images.simplywall.st/company/2bb88255-5b25-4ce7-bb16-867fff68cc39/chart/dcf"/><figcaption>IRON Discounted Cash Flow as at Nov 2025</figcaption></figure><p>Simply Wall St performs a discounted cash flow (DCF) on every stock in the world every day (check out Disc Medicine for example). We show the entire calculation in full. You can track the result in your watchlist or portfolio and be alerted when this changes, or use our stock screener to discover 879 undervalued stocks based on their cash flows. If you save a screener we even alert you when new companies match - so you never miss a potential opportunity.</p> <h2> Build Your Own Disc Medicine Narrative</h2> <p>If you would rather arrive at your own conclusions or want to dig deeper into Disc Medicine’s figures, you can easily craft a personalized analysis in just a few minutes. Do it your way</p> <p>A great starting point for your Disc Medicine research is our analysis highlighting 2 key rewards and 3 important warning signs that could impact your investment decision.</p> <h2>Looking for more investment ideas?</h2> <p>Don’t let unique opportunities slip by. Expand your search and power up your portfolio by targeting standout stocks with compelling stories and strong potential.</p> <ul> <li>Tap into high-growth potential by checking out these 3593 penny stocks with strong financials driving transformation in dynamic market sectors this year.</li> <li>Capitalize on the AI revolution and get ahead of trends with these 25 AI penny stocks shaping innovation across industries.</li> <li>Strengthen your passive income strategy through these 16 dividend stocks with yields &gt; 3% that currently offer attractive yields and solid fundamentals.</li> </ul> <p><em> This article by Simply Wall St is general in nature. <strong>We provide commentary based on historical data     and analyst forecasts only using an unbiased methodology and our articles are not intended to be financial advice.</strong> It does not constitute a recommendation to buy or sell any stock, and does not take account of your objectives, or your     financial situation. We aim to bring you long-term focused analysis driven by fundamental data.     Note that our analysis may not factor in the latest price-sensitive company announcements or qualitative material.     Simply Wall St has no position in any stocks mentioned.</em></p></div></div>

IRON

<p>Disc Medicine (IRON) has launched a Phase 1b trial for its sickle cell disease therapy and received FDA priority review for bitopertin. The stock has surged 51.3% in the past year. The company's P/B ratio is 5.9x, higher than the industry average but lower than peers. A DCF model suggests a fair value of $100.52, indicating potential undervaluation. Risks include disappointing clinical results and competitive developments.</p>

Disc Medicine (IRON): Valuation Insights Following FDA Priority Review and New Clinical Trial Launch